Distinct variant of Sweet's syndrome: bortezomib-induced histiocytoid Sweet's syndrome in a patient with multiple myeloma

Abstract

Histiocytoid Sweet’s syndrome (SS) is a rare variant ofthe acute febrile neutrophilic dermatosis recentlydescribed.1It is characterized by an infiltrate of immaturemyeloid cells.1Only one case of histiocytoid SS inducedby bortezomib in multiple myeloma has been reported inthe dermatologic literature.2Herein, we present a case of bortezomib-induced histio-cytoid SS in a patient with multiple myeloma followinga course of bortezomib, along with a review of theliterature