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Chemical Reaction-Induced Multi-molecular Polarization (CRIMP)
- Title
- Chemical Reaction-Induced Multi-molecular Polarization (CRIMP)
- Author
- 이영복
- Keywords
- pyruvic acid; acetic acid derivative; carbon; fatty acid; Article; carbon nuclear magnetic resonance; chemical reaction; chemical reaction induced multi molecular polarization; citric acid cycle; decarboxylation; dissolution; fatty acid synthesis; hyperpolarization; magnetic field; nuclear magnetic resonance; pH; solid state; chemistry; glycolysis; nuclear magnetic resonance imaging; nuclear magnetic resonance spectroscopy; synthesis
- Issue Date
- 2014-09
- Publisher
- Royal Society of Chemistry
- Citation
- Chemical communications, 2014, 50(86), P.13030-13033
- Abstract
- Here we present a novel hyperpolarization method, Chemical Reaction-Induced Multi-molecular Polarization (CRIMP), which could be applied to the study of several in vivo processes simultaneously including glycolysis, TCA cycle, fatty acid synthesis and pH mapping. Through the use of non-enzymatic decarboxylation, we generate four hyperpolarized imaging agents from hyperpolarized 1,2- 13 C pyruvic acid. Graphic Abstract Here we present a novel hyperpolarization method, Chemical Reaction-Induced Multi-molecular Polarization (CRIMP), which could be applied to the study of several in vivo processes simultaneously including glycolysis, TCA cycle, fatty acid synthesis and pH mapping.
- URI
- http://pubs.rsc.org/en/content/articlelanding/2014/cc/c4cc06199c#!divAbstracthttp://hdl.handle.net/20.500.11754/52400
- ISSN
- 1359-7345; 1364-548X
- Appears in Collections:
- GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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