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Gaps between global guidelines and local practices in CKD-MBD

Title
Gaps between global guidelines and local practices in CKD-MBD
Author
김근호
Keywords
Calcium; Hemodialysis; Mortality; Parathyroid hormone; Phosphorus
Issue Date
2014-12
Publisher
대한전해질학회
Citation
Electrolytes & Blood Pressure, 권: 12. 호: 2, 페이지: 35-40
Abstract
The term 'chronic kidney disease-mineral bone disorder' (CKD-MBD) is a new term that, in contrast to the old term 'renal osteodystrophy', implies a systemic syndrome associated with cardiovascular morbidity and mortality. This new terminology is in line with previous studies that show elevated serum calcium, phosphorus, and parathyroid hormone (PTH) levels associated with increased cardiovascular and all-cause mortality. In order to improve outcomes in patients with CKD-MBD, many countries have developed clinical practice guidelines. Globally, the Kidney Disease Outcome Quality Initiative (KDOQI) and Kidney Disease: Improving Global Outcomes (KDIGO) guidelines are the most commonly used. However, whether these global guidelines can be successfully implemented on a local level needs to be studied. Differences in medical care and social factors between countries may limit the generalizability of global guidelines. Reports from the Korean registry and the Dialysis Outcomes and Practice Patterns Study (DOPPS) suggest that many dialysis patients are not within the target ranges recommended by the KDOQI and KDIGO guidelines for serum calcium, phosphorus, and PTH, suggesting gaps between global guidelines and local practices. Clinical studies with Korean CKD-MBD patients are necessary to compare Korean practices and outcomes to those suggested by global guidelines and to determine the target serum mineral levels associated with the best local outcomes.
URI
https://synapse.koreamed.org/search.php?where=aview&id=10.5049/EBP.2014.12.2.35&code=0158EBP&vmode=FULLhttp://hdl.handle.net/20.500.11754/51976
ISSN
1738-5997
DOI
10.5049/EBP.2014.12.2.35
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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