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dc.contributor.author이양순-
dc.date.accessioned2018-03-24T01:04:05Z-
dc.date.available2018-03-24T01:04:05Z-
dc.date.issued2013-10-
dc.identifier.citationDIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2013, 77(2), P.160-163en_US
dc.identifier.issn0732-8893-
dc.identifier.issn1879-0070-
dc.identifier.urihttps://ac.els-cdn.com/S0732889313003416/1-s2.0-S0732889313003416-main.pdf?_tid=dca52c78-d6ca-4546-8302-7299d34dfb87&acdnat=1520859393_ea55767f6957dbfdbb80f7e2b495606a-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/51694-
dc.description.abstractCarbapenem-resistant Acinetobacter spp. have been increasingly reported worldwide with the production of OXA-type carbapenemases as the main mechanism of carbapenem resistance. The prevalent bla(OXA) genes are known to vary significantly depending on time and place of isolation. We investigated the prevalence of bla(OXA) genes by PCR in Acinetobacter spp. isolated in Korea. Among a total of 336 isolates collected from Hospital A from 2002 to 2011, the overall proportion of bla(OXA-23)-like, ISAba1-associated bla(OXA-51)-like, and bla(OXA-182) genes were 44.0%, 49.7%, and 5.1%, respectively. The bla(OXA-58)-like gene was detected in only 1 isolate. A drastic increase in Acinetobacter isolates with bla(OXA-23)-like genes and a decrease in isolates harboring ISAba1-associated bla(OXA-51)-like genes have been observed since the mid-2000s. The bla(OXA-23)-like genes were detected in all carbapenem-nonsusceptible isolates collected in 2011 from 9 hospitals. The OXA-182, which belongs to the fifth group of OXA-type carbapenemase, was detected in Acinetobacter baumannii isolates recovered as early as 2002. It is worrisome results that bla(OXA-182)-carrying Acinerobacter nosocomialis has emerged and caused outbreaks of infection. (C) 2013 Elsevier Inc. All rights reserved.en_US
dc.description.sponsorshipThe authors thank Myung Sook Kim and Yong Hee Seo, Clinical Microbiology and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, for collecting the isolates and for technical assistance.en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USAen_US
dc.subjectbla(OXA-182)en_US
dc.subjectbla(OXA-23)en_US
dc.subjectAcinetobacter nosocomialisen_US
dc.subjectAcinetobacter baumanniien_US
dc.subjectOXA CARBAPENEMASESen_US
dc.subjectSPP.en_US
dc.subjectGENESen_US
dc.subjectDISSEMINATIONen_US
dc.subjectEXPRESSIONen_US
dc.subjectPCRen_US
dc.titleIncreasing prevalence of bla(OXA-23)-carrying Acinetobacter baumannii and the emergence of bla(OXA-182)-carrying Acinetobacter nosocomialis in Koreaen_US
dc.typeArticleen_US
dc.relation.volume77-
dc.identifier.doi10.1016/j.diagmicrobio.2013.06.009-
dc.relation.page160-163-
dc.relation.journalDIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE-
dc.contributor.googleauthorLee, Yangsoon-
dc.contributor.googleauthorKim, Young-Ree-
dc.contributor.googleauthorKim, Jayoung-
dc.contributor.googleauthorPark, Yeon-Joon-
dc.contributor.googleauthorSong, Wonkeun-
dc.contributor.googleauthorShin, Jong-Hee-
dc.contributor.googleauthorUh, Young-
dc.contributor.googleauthorLee, Kyutaeg-
dc.contributor.googleauthorLee, Seong Hee-
dc.contributor.googleauthorCho, Ji Hyun-
dc.relation.code2013009688-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidyangsoon-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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