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dc.contributor.author전대원-
dc.date.accessioned2018-03-23T07:47:03Z-
dc.date.available2018-03-23T07:47:03Z-
dc.date.issued2014-11-
dc.identifier.citation대한소화기학회지, 권: 64, 호: 4, 페이지: 182-188en_US
dc.identifier.issn1598-9992-
dc.identifier.urihttps://www.synapse.koreamed.org/search.php?where=aview&id=10.4166/kjg.2014.64.4.182&code=0028KJG&vmode=FULL-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/51551-
dc.description.abstractCell death is an integral part of life of an organism that is necessary to maintain organs and tissues. Apoptosis, autophagy, and necrosis were noted as three morphologically distinct types of cell death. Apoptosis is a well identified process that is driven by programmed molecular mechanism. Until now, the investigators believed that necrosis was not a programmed molecular event. However, recently, an alternative death pathway called 'necroptosis' was delineated and proposed as a form of 'programmed necrosis'. According to the recent recommendations by the Nomenclature Committee of Cell Death, this term denotes necrotic cell death dependent on receptor-interacting protein kinase (RIPK3). Its role in a variety of diseases, such as ischemia-perfusion injury, infection, inflammatory bowel disease, pancreatitis, steatohepatitis etc., is being elucidated. Necroptosis is currently attracting the attention of the scientific community. Herein we discuss the clinical implications and the role of necroptosis in gastrointestinal tract focusing on liver and pancreatic diseases.en_US
dc.language.isoenen_US
dc.publisherThe Korean Society Of Gastroenterologyen_US
dc.subjectCell deathen_US
dc.subjectNecroptosisen_US
dc.subjectNecrosisen_US
dc.subjectReceptor-interacting protein kinaseen_US
dc.subjectTumor necrosis factor-alphaen_US
dc.titleNecroptosis in Liver and Pancreatic Diseasesen_US
dc.title.alternative간, 췌장 질환에서 Necroptosisen_US
dc.typeArticleen_US
dc.relation.no4-
dc.relation.volume64-
dc.identifier.doi10.4166/kjg.2014.64.4.182-
dc.relation.page182-188-
dc.relation.journalThe Korean journal of gastroenterology-
dc.contributor.googleauthor윤재훈-
dc.contributor.googleauthor전대원-
dc.contributor.googleauthor최호순-
dc.relation.code2012211627-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidnoshin-


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