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Nasal and Exhaled Nitric Oxide in Allergic Rhinitis

Title
Nasal and Exhaled Nitric Oxide in Allergic Rhinitis
Author
조석현
Keywords
Nitirc oxide; Nasal nitric oxide; Exhaled nitric oxide; Allergic rhinitis; Asthma
Issue Date
2012-12
Publisher
대한이비인후과학회
Citation
Clinical and Experimental Otorhinolaryngology, 2012, 5(4), P.228-233, 6P.
Abstract
Objectives. The primary aim of this study was to assess whether one can use levels of nasal nitric oxide (nNO) and exhalednitric oxide (eNO) as a means of evaluation in allergic rhinitis.Methods. We used a chemiluminescence analyzer to measure nNO and eNO in normal controls (n=34) and allergic rhinitispatients (n=35), and compared these measurements with various parameters of clinical symptoms and laboratory data.Results. Mean nNO (389±119 ppb) in allergic rhinitis patients was significantly higher than normal controls (276±88 ppb).Without asthma, mean eNO (64.8±55.9 ppb) in allergic rhinitis patients was significantly higher than normal controls(33.0±24.0 ppb). In the persistent allergic rhinitis group, eNO concentration was significantly higher, while nNOconcentration was significantly lower than the intermittent group.Conclusion. We can use nNO and eNO levels for evaluation of allergic rhinitis. However, we should consider the fact thatnNO levels can be reduced, when symptoms are severe and long-lasting. Additionally, in allergic rhinitis, eNO can beelevated without asthma.
URI
https://www.e-ceo.org/journal/view.php?doi=10.3342/ceo.2012.5.4.228http://hdl.handle.net/20.500.11754/51139
ISSN
1976-8710; 2005-0720
DOI
10.3342/ceo.2012.5.4.228
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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