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Glycosylated Hemoglobin Threshold for Predicting Diabetes and Prediabetes from the Fifth Korea National Health and Nutrition Examination Survey.

Title
Glycosylated Hemoglobin Threshold for Predicting Diabetes and Prediabetes from the Fifth Korea National Health and Nutrition Examination Survey.
Author
이창범
Keywords
Diabetes mellitus; Diagnosis; Hemoglobin A; Glycosylated
Issue Date
2016-04
Publisher
Korean Diabetes Association
Citation
Diabetes and Metabolism Journal, v. 40, NO 2, Page. 167-170
Abstract
We aimed to estimate the threshold level of glycosylated hemoglobin (HbA1c) for the fasting plasma glucose of 100 and 126 mg/dL in the Korean adult population, using the 2011 Korea National Health and Nutrition Examination Survey. A total of 4,481 participants over 19 years of age without diabetic medications and conditions to influence the interpretation of HbA1c levels, such as anemia, renal insufficiency, liver cirrhosis, and cancers, were analyzed. A point-wise area under the receiver operating characteristic curve was used to estimate the optimal HbA1c cutoff value. A HbA1c threshold of 6.35% was optimal for predicting diabetes with a sensitivity of 86.9% and a specificity of 99.1%. Furthermore, the threshold of HbA1c was 5.65% for prediabetes, with a sensitivity of 69.3% and a specificity of 71%. Further prospective studies are needed to evaluate the HbA1c cutoff point for diagnosing prediabetes and diabetes in the Korean population.
URI
https://synapse.koreamed.org/DOIx.php?id=10.4093/dmj.2016.40.2.167http://hdl.handle.net/20.500.11754/50180
ISSN
2233-6079; 2233-6087
DOI
10.4093/dmj.2016.40.2.167
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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