Manegement of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Abstract

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition; however, many of the traditional therapies like monotherapy used in clinical practice fail to show efficacy. There is no one particular treatment to be recommended as a mono-therapy for CP/CPPS. New concept of treatment which is `UPOINT' is introduced. The major barrier in treating men with CP/CPPS is the heterogenous nature of this syndrome.In order to treat appropriately patient should be evaluated individually to assess the nature of symptoms. To evaluate patients chronic urologic pelvic pain, six-point clinical phenotyping system is developed. The clinical domains are urinary symptoms, psychosocial dysfunction, organ-specific findings, infection, neurologic/systemic, and tenderness of muscles, which produces the acronym UPOINT. This clinical phenotyping system may provide a useful and clinically relevant framework for multimodal therapy for the treatment of CP/CPPS. However, concept of UPOINT needs randomization, placebo or sham control studies to show verified treatment.