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dc.contributor.author김인영-
dc.date.accessioned2018-03-20T05:37:01Z-
dc.date.available2018-03-20T05:37:01Z-
dc.date.issued2013-03-
dc.identifier.citationPHYSIOLOGICAL MEASUREMENTl, 2013, 34(3), p.N15-N24en_US
dc.identifier.issn0967-3334-
dc.identifier.urihttp://iopscience.iop.org/article/10.1088/0967-3334/34/3/N15/meta-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/49549-
dc.description.abstractIn this study, we analyzed the waveform characteristics of resting tremor by accelerometer recordings in patients with drug-induced parkinsonism (DIP) and Parkinson's disease (PD). We prospectively recruited 12 patients with tremulous PD and 12 patients with DIP presenting with resting tremor. Tremor was recorded from the more affected side and was recorded twice for a 60 s period in each patient. Peak frequency, amplitude and all harmonic peaks were obtained, and the asymmetry of the decay of the autocorrelation function, third momentum and time-reversal invariance were also computed using a mathematical algorithm. Among the parameters used in the waveform analysis, the harmonic ratio, time-reversal invariance and asymmetric decay of the autocorrelation function were different between PD and DIP at a statistically significant level (all p < 0.01). The total harmonic peak power and third momentum in the time series were not significantly different. The clinical characteristics of DIP patients may be similar to those of PD patients in some cases, which makes the clinical differentiation between DIP and PD challenging. Our study shows that the identification of parameters reflecting waveform asymmetry might be helpful in differentiating between DIP and PD.en_US
dc.description.sponsorshipThis work was supported by a grant from the Korean Health Technology R&D Project, Ministry for Health Welfare & Family Affairs, Republic of Korea (A101712).en_US
dc.language.isoenen_US
dc.publisherIOP PUBLISHING LTD, TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLANDen_US
dc.subjectParkinson's diseaseen_US
dc.subjectdrug-induced parkinsonismen_US
dc.subjecttremoren_US
dc.subjectaccelerometryen_US
dc.subjectFOLLOW-UPen_US
dc.subjectPATHOPHYSIOLOGYen_US
dc.subjectSCINTIGRAPHYen_US
dc.subjectPETen_US
dc.titleWaveform analysis of tremor may help to differentiate Parkinson's disease from drug-induced parkinsonismen_US
dc.typeArticleen_US
dc.relation.no3-
dc.relation.volume34-
dc.identifier.doi10.1088/0967-3334/34/3/N15-
dc.relation.page15-24-
dc.relation.journalPHYSIOLOGICAL MEASUREMENT-
dc.contributor.googleauthorJang, W-
dc.contributor.googleauthorHan, J-
dc.contributor.googleauthorPark, J-
dc.contributor.googleauthorKim, JS-
dc.contributor.googleauthorCho, JW-
dc.contributor.googleauthorKoh, SB-
dc.contributor.googleauthorChung, SJ-
dc.contributor.googleauthorKim, IY-
dc.contributor.googleauthorKim, HT-
dc.relation.code2013011706-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidiykim-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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