Preparation of SERS active Ag nanoparticles encapsulated by phospholipids
- Title
- Preparation of SERS active Ag nanoparticles encapsulated by phospholipids
- Author
- 윤종승
- Keywords
- phospholipid; self?assembly; nanoparticles; surface?enhanced Raman spectroscopy; Raman reporter
- Issue Date
- 2014-03
- Publisher
- John Wiley & Sons, Ltd
- Citation
- Journal of Raman spectroscopy, Vol.45 No.4 [2014], pp. 292-298
- Abstract
- A cost-effective way of fabricating lipid-coated surface-enhanced Raman spectroscopy (SERS) substrate having reproducible high SERS activity was proposed. Ag nanoparticle embedded in 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) membranes was produced by direct deposition of a 5-nm-thick layer of Ag onto the solid-supported phospholipid membrane, and subsequent dissolution of the Ag nanoparticle-embedded membrane in iso-octane allowed easy one-pot fabrication of DOPC- or DOTAP-coated Ag nanoparticles. In particular, DOTAP produced nearly monodisperse lipid-encapsulated Ag nanoparticles (9nm in diameter) exhibiting reproducible high SERS activity (detecting up to 10nM of rhodamine 6G and 0.5M of glutathione). In addition, the process was modified to incorporate variety of Raman active molecules (rhodamine 6G, malachite green, 4-aminothiopheonol, 4-mercaptopyridine) into the particle-encapsulating lipid bilayer. The DOTAP/Raman dye-coated Ag nanoparticles also generated high SERS activity to enable potential application of the DOTAP/Raman dye-coated Ag nanoparticles feasible in different areas. Copyright (C) 2014 John Wiley & Sons, Ltd.
- URI
- http://onlinelibrary.wiley.com/doi/abs/10.1002/jrs.4461http://hdl.handle.net/20.500.11754/49515
- ISSN
- 0377-0486
- DOI
- 10.1002/jrs.4461
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > MATERIALS SCIENCE AND ENGINEERING(신소재공학부) > Articles
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML