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dc.contributor.author유혜현-
dc.date.accessioned2018-03-19T02:25:23Z-
dc.date.available2018-03-19T02:25:23Z-
dc.date.issued2016-01-
dc.identifier.citationEUROPEAN FOOD RESEARCH AND TECHNOLOGY, v. 242, No. 1, Page. 137-142en_US
dc.identifier.issn1438-2377-
dc.identifier.issn1438-2385-
dc.identifier.urihttps://link.springer.com/article/10.1007/s00217-015-2519-6-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/48708-
dc.description.abstract6-Shogaol [(4E)-1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one] is a pungent and bioactive ingredient of ginger. This study investigated the biotransformation of 6-shogaol by Aspergillus niger. 6-Shogaol was fermented by A. niger, and the resultant metabolites were structurally characterized by liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF MS). As a result, 6-shogaol was biotransformed to yield metabolites: M1, M2 (6-paradol), M3, and M4. The major metabolic routes were reduction and hydroxylation; the carbonyl group and double bond of 6-shogaol were reduced to generate M1 and M2, respectively, which were further hydroxylated or reduced to M3 and M4. Among these metabolites, M1 was reported for the first time in this study.en_US
dc.description.sponsorshipThis research was supported by Bio-industry Technology Development Program, Ministry of Agriculture, Food and Rural Affairs (112136-4).en_US
dc.language.isoen_USen_US
dc.publisherSPRINGERen_US
dc.subjectGingeren_US
dc.subject6-Shogaolen_US
dc.subjectAspergillus nigeren_US
dc.subjectBiotransformationen_US
dc.subjectLC-QTOF MSen_US
dc.subjectZINGIBER-OFFICINALE ROSCOEen_US
dc.subjectGINGERen_US
dc.subjectCONSTITUENTSen_US
dc.subjectSHOGAOLSen_US
dc.subjectEXTRACTen_US
dc.subjectANALOGSen_US
dc.titleCharacterization of metabolites produced from the biotransformation of 6-shogaol formed by Aspergillus nigeren_US
dc.typeArticleen_US
dc.relation.no1-
dc.relation.volume242-
dc.identifier.doi10.1007/s00217-015-2519-6-
dc.relation.page137-142-
dc.relation.journalEUROPEAN FOOD RESEARCH AND TECHNOLOGY-
dc.contributor.googleauthorJo, Soo Kyung-
dc.contributor.googleauthorKim, In Sook-
dc.contributor.googleauthorRehman, Shaheed Ur-
dc.contributor.googleauthorHa, Sang Keun-
dc.contributor.googleauthorPark, Ho-Young-
dc.contributor.googleauthorPark, Yong Kon-
dc.contributor.googleauthorYoo, Hye Hyun-
dc.relation.code2016002889-
dc.sector.campusE-
dc.sector.daehakCOLLEGE OF PHARMACY[E]-
dc.sector.departmentDEPARTMENT OF PHARMACY-
dc.identifier.pidyoohh-
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COLLEGE OF PHARMACY[E](약학대학) > ETC
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