123 0

Characterization of metabolites produced from the biotransformation of 6-shogaol formed by Aspergillus niger

Title
Characterization of metabolites produced from the biotransformation of 6-shogaol formed by Aspergillus niger
Author
유혜현
Keywords
Ginger; 6-Shogaol; Aspergillus niger; Biotransformation; LC-QTOF MS; ZINGIBER-OFFICINALE ROSCOE; GINGER; CONSTITUENTS; SHOGAOLS; EXTRACT; ANALOGS
Issue Date
2016-01
Publisher
SPRINGER
Citation
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, v. 242, No. 1, Page. 137-142
Abstract
6-Shogaol [(4E)-1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one] is a pungent and bioactive ingredient of ginger. This study investigated the biotransformation of 6-shogaol by Aspergillus niger. 6-Shogaol was fermented by A. niger, and the resultant metabolites were structurally characterized by liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF MS). As a result, 6-shogaol was biotransformed to yield metabolites: M1, M2 (6-paradol), M3, and M4. The major metabolic routes were reduction and hydroxylation; the carbonyl group and double bond of 6-shogaol were reduced to generate M1 and M2, respectively, which were further hydroxylated or reduced to M3 and M4. Among these metabolites, M1 was reported for the first time in this study.
URI
https://link.springer.com/article/10.1007/s00217-015-2519-6http://hdl.handle.net/20.500.11754/48708
ISSN
1438-2377; 1438-2385
DOI
10.1007/s00217-015-2519-6
Appears in Collections:
COLLEGE OF PHARMACY[E](약학대학) > ETC
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE