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Frequency and pattern of central lymph node metastasis in papillary carcinoma of the thyroid isthmus

Title
Frequency and pattern of central lymph node metastasis in papillary carcinoma of the thyroid isthmus
Author
지용배
Keywords
thyroid neoplasm; papillary thyroid carcinoma; thyroid isthmus; lymph node dissection; lymphatic metastasis
Issue Date
2016-04
Publisher
WILEY-BLACKWELL
Citation
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, v. 38, Page. 412-416
Abstract
Background. The purpose of this study was to evaluate the frequency and pattern of central lymph node metastasis in isthmic papillary thyroid carcinoma (PTC). Methods. We compared the clinical and pathological data of 45 patients with a single isthmic PTC and 149 patients with a single PTC located in the unilateral thyroid lobe, all of whom underwent total thyroidectomy and bilateral central neck dissection. Results. The rates of clinical, pathologic, and occult central lymph node metastasis were higher in the isthmus group than the non-isthmus group. Central lymph node metastasis in the pretracheal and bilateral paratracheal lymph nodes was more frequent in the isthmic PTC group than in the non-isthmus group. On multivariate analysis, isthmic location of the tumor was an independent risk factor for central lymph node metastasis. Conclusion. Complete bilateral central neck dissection should be considered for isthmic PTC because of the high rate of bilateral central lymph node metastasis, especially to pretracheal and bilateral paratracheal lymph nodes. (C) 2015 Wiley Periodicals, Inc.
URI
http://onlinelibrary.wiley.com/doi/10.1002/hed.24009/abstract;jsessionid=3E6B41B33CDBDDB4E6798F6FD27943DB.f04t01http://hdl.handle.net/20.500.11754/47619
ISSN
1043-3074; 1097-0347
DOI
10.1002/hed.24009
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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