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A case of chronic myeloid leukemia with features of essential thrombocythemia in peripheral blood and bone marrow

Title
A case of chronic myeloid leukemia with features of essential thrombocythemia in peripheral blood and bone marrow
Author
박병배
Keywords
Chronic myeloid leukemia; Philadelphia chromosome; Essential thrombocythemia
Issue Date
2014-06
Publisher
대한혈액학회
Citation
Blood Research, 권: 49, 호: 2, 페이지: 127-129
Abstract
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by over-production of myeloid white blood cells. Philadelphia chromosome is an essential finding for CML diagnosis. Generally, a clinical diagnosis of essential thrombocythemia (ET) can be established from isolated marked thrombocytosis in peripheral blood. However, Philadelphia chromosome-positivity or bcr/abl rearrangement with isolated thrombocy-tosis should be diagnosed as CML, not ET, according to World Health Organization diag-nostic criteria. Therefore, CML should not be excluded before confirming the presence of the Philadelphia chromosome or bcr/abl rearrangement in cases of isolated thrombocy-tosis in peripheral blood. We report a case of CML with clinical features of ET in a patient successfully treated with imatinib.
URI
https://www.synapse.koreamed.org/search.php?where=aview&id=10.5045/br.2014.49.2.127&code=3072BR&vmode=FULLhttp://hdl.handle.net/20.500.11754/47329
ISSN
2287-979X
DOI
10.5045/br.2014.49.2.127
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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