Toxicology study with microRNA

Title
Toxicology study with microRNA
Author
황승용
Keywords
microRNA; miRNA; Toxicology; Toxicoepigenomics; Epigenomics
Issue Date
2014-06
Publisher
KOREAN SOCIETY TOXICOGENOMICS & TOXICOPROTEOMICS-KSTT, HANYANG UNIV, SCI & TECHNOL BLDG 1, RM 423, SA-DONG, SANGROK-GU, ANSAN, GYEONGGI-DO, 426 791, SOUTH KOREA
Citation
MOLECULAR & CELLULAR TOXICOLOGY, 권: 10, 호: 2, 페이지: 127-134
Abstract
microRNAs have a principal role in many biological processes, such as gene expression, control and development, as well as cellular processes. In recent years, microRNAs have attracted great interest in the field of toxicology. When organisms are exposed to toxic compounds, microRNAs expression is altered, which affects mRNA transcription and protein translation and causes adverse biological effects. Here, we introduce microRNAs as research tools, the specific expression profile of microRNAs following exposure to different toxicants or diseases that were found to be sensitive biomarkers. Finally, we address several issues related to microRNAs in toxicological studies.
URI
http://link.springer.com/article/10.1007%2Fs13273-014-0014-yhttp://hdl.handle.net/20.500.11754/46577
ISSN
1738-642X; 2092-8467
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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