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Risk Factors for Acute Hepatitis A Infection in Korea in 2007 and 2009: A Case-Control Study

Title
Risk Factors for Acute Hepatitis A Infection in Korea in 2007 and 2009: A Case-Control Study
Author
전대원
Keywords
Case-Control Studies; Hepatitis A; Korea; Risk Factors
Issue Date
2013-06
Publisher
대한의학회
Citation
J Korean Med Sci, 2013 Jun, 28(6), p.908-914
Abstract
This study aimed to identify the risk factors associated with acute hepatitis A virus (HAV)infection in the Korean population. Participants were recruited from five referral hospitals across the country in 2007 and from 11 hospitals in 2009. Patients with positive anti-HAV IgM antibody tests became the case group, while patients treated for non-contagious diseases at the same hospitals were recruited as controls. A total of 222 and 548 casecontrol pairs were studied in the 2007 and 2009 surveys, respectively. Data from the surveys were analyzed jointly. In a multivariate analysis, sharing the household with HAVinfected family members (OR, 6.32; 95% CI, 1.4-29.6), contact with other HAV-infected individuals (OR, 4.73; 95% CI, 2.4-9.4), overseas travel in 2007 (OR, 19.93; 95% CI, 2.3-174.4), consumption of raw shellfish (OR, 2.51; 95% CI, 1.8-3.5), drinking bottled water (OR, 1.64; 95% CI, 1.3-8.4), and occupation that involve handling food (OR, 3.30; 95%CI, 1.3-8.4) increased the risk of HAV infection. Avoiding contact with HAV-infected individuals and avoiding raw foods eating could help minimize the risk of hepatitis A infection. Immunization must be beneficial to individuals who handle food ingredients occupationally or travel overseas to HAV-endemic areas.
URI
https://www.synapse.koreamed.org/search.php?where=aview&id=10.3346/jkms.2013.28.6.908&code=0063JKMS&vmode=FULLhttp://hdl.handle.net/20.500.11754/46556
ISSN
1011-8934; 1598-6357
DOI
10.3346/jkms.2013.28.6.908
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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