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The Primary Extra-gastrointestinal Stromal Tumor of Pleura: A Case Report and a Literature Review

Title
The Primary Extra-gastrointestinal Stromal Tumor of Pleura: A Case Report and a Literature Review
Author
백승삼
Keywords
gastrointestinal stromal tumor; pleural cavity; KIT; DOG-1; Thoracic-Mediastinum; pleura
Issue Date
2013-11
Publisher
Oxford University Press
Citation
Japanese Journal of Clinical Oncology, Vol.43, No.12 [2013], p1269-1272
Abstract
The gastrointestinal stromal tumor is the most common mesenchymal neoplasm of the gastrointestinal tract. The gastrointestinal stromal tumor universally expresses KIT and DOG-1 and frequently harbors oncogenic mutations in the KIT gene. While the gastrointestinal stromal tumor usually arises in the alimentary tract, it is rarely found in the extragastrointestinal area. When it is, it is called an extragastrointestinal stromal tumor. Although the pathogenesis, prognostic factors and outcomes of gastrointestinal stromal tumors are well known, those of extragastrointestinal stromal tumors have not been fully studied. We report, herein, a unique primary extragastrointestinal stromal tumor from the pleura in a 73-year-old woman who presented with pleural mass. The extragastrointestinal stromal tumor was surgically resected and confirmed by means of an immunohistochemical study and a molecular analysis.
URI
http://academic.oup.com/jjco/article/43/12/1269/891912http://hdl.handle.net/20.500.11754/46212
ISSN
0368-2811
DOI
10.1093/jjco/hyt158
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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