Effect of the corrective osteotomy in ankylosing spondylitis to quality of life(QOL)

Abstract

Study Design:This is retrospective study.Objective:We evaluated the radiologic changes and quality of life after corrective osteotomy in kyphotic deformity of ankylosing spondylitis.Summary of Literature Review:There is few study about that relationship between corrective osteotomy and quality of life.Materials and Methods:Retrospective study about 16 patients who underwent corrective osteotomy from 2005 September to 2007 December was done. Radiologic assessments of sagittal balance were performed on the criteria of thoracic kyphosis, lumbar lordosis, distance between the vertical line on midpoint of C7 and posterosuperior point of S1 pre and postoperatively. Disease specific instruments: the Bath ankylosing spondylitis disease activity index (BASDAI) and the Bath ankylosing spondylitis functional index (BASFI) were applied. Clinical assessments were performed with short form-36 through interview and telephone.Results:The mean thoracic kyphosis was changed from 46.1 degrees to 39.3 degrees. The mean lumbar lordosis was corrected from - 7.4 degrees to - 38.4 degrees, and the mean distance between vertical lines of C7 and S1 was improved from 127.1mm to 30mm. There were significant changes in the subgroup of Physical function, Role physical, Vitality, Social function, Role emotional, Mental health. (p<0.05) The changes of BASDAI, BASFI, Bodily pain and General health were not significant. And similar improvements in the radiological results and SF-36 scores were in the 6 patients with Andersson lesion.Conclusion:The parameters of radiographic assessment were improved after corrective osteotomy in the fixed kyphotic deformity of ankylosing spondylitis. General function, social function and mental health were also improved.