One-step detection of melamine in milk by hollow gold chip based on surface-enhanced Raman scattering

Title
One-step detection of melamine in milk by hollow gold chip based on surface-enhanced Raman scattering
Author
주재범
Keywords
Surface-enhanced Raman scattering; Hollow gold nanospheres; Melamine; Milk; Hot spot
Issue Date
2014-05
Publisher
ELSEVIER SCIENCE BV
Citation
Talanta, 2014, 122, pp.80 - 84
Abstract
A hollow gold (HG) chip with high surface-enhanced Raman scattering (SERS) capability was fabricated and used to monitor the adulteration of milk with melamine. This chip was fabricated with self-assembled hollow gold nanospheres (HGNs) on glass wafers through electrostatic interaction. There are two important advantages for the use of this HG chip as a detection platform. First, HGNs show a strong SERS enhancement from individual particles due to their capability to localize the electromagnetic fields around the pinholes in hollow shells. Second, the HG chip improves the limit of detection through the enrichment effect. The characteristic SERS peak of melamine was used to distinguish it from other kinds of proteins or amino acids, and its intensity was used to monitor the percentage of melamine in milk. With its simple detection procedure (no pretreatment or separation steps), decreased processing time and low detection limit, this HG chip shows a strong potential for broad applications in melamine detection from real samples. (c) 2014 Elsevier B.V. All rights reserved.
URI
https://www.sciencedirect.com/science/article/pii/S003991401400054X?via%3Dihubhttp://hdl.handle.net/20.500.11754/45858
ISSN
0039-9140
DOI
10.1016/j.talanta.2014.01.043
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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