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dc.contributor.author심지원-
dc.date.accessioned2018-03-13T02:19:03Z-
dc.date.available2018-03-13T02:19:03Z-
dc.date.issued2013-12-
dc.identifier.citationDEVELOPMENT, 140, 23, p4647-p4656en_US
dc.identifier.issn0950-1991-
dc.identifier.urihttp://dev.biologists.org/content/140/23/4647.short-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/45770-
dc.description.abstractStem cells and their progenitors are maintained within a microenvironment, termed the niche, through local cell-cell communication. Systemic signals originating outside the niche also affect stem cell and progenitor behavior. This review summarizes studies that pertain to nutritional effects on stem and progenitor cell maintenance and proliferation in Drosophila. Multiple tissue types are discussed that utilize the insulin-related signaling pathway to convey nutritional information either directly to these progenitors or via other cell types within the niche. The concept of systemic control of these cell types is not limited to Drosophila and may be functional in vertebrate systems, including mammals.en_US
dc.description.sponsorshipU.B. is supported by the National Institutes of Health and by the UCLA Broad Stem Cell Research Center (BSCRC). J.S. is supported by a California Institute for Regenerative Medicine (CIRM) postdoctoral training grant and by a training grant from the BSCRC. Deposited in PMC for release after 12 months.en_US
dc.language.isoenen_US
dc.publisherCOMPANY OF BIOLOGISTS LTDen_US
dc.subjectDrosophilaen_US
dc.subjectInsulinen_US
dc.subjectDilpen_US
dc.subjectGermline stem cellen_US
dc.subjectIntestinal stem cellen_US
dc.subjectHematopoietic progenitor cellen_US
dc.subjectNeural stem cellen_US
dc.subjectAmino acid sensingen_US
dc.subjectNutritional controlen_US
dc.titleNutritional regulation of stem and progenitor cells in Drosophilaen_US
dc.typeArticleen_US
dc.relation.no23-
dc.relation.volume140-
dc.identifier.doi10.1242/dev.079087-
dc.relation.page4647-4656-
dc.relation.journalDEVELOPMENT-
dc.contributor.googleauthorShim, Jiwon-
dc.contributor.googleauthorGururaja-Rao, Shubha-
dc.contributor.googleauthorBanerjee, Utpal-
dc.relation.code2013009669-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF NATURAL SCIENCES[S]-
dc.sector.departmentDEPARTMENT OF LIFE SCIENCE-
dc.identifier.pidjshim-
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COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
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