Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 심지원 | - |
dc.date.accessioned | 2018-03-13T02:19:03Z | - |
dc.date.available | 2018-03-13T02:19:03Z | - |
dc.date.issued | 2013-12 | - |
dc.identifier.citation | DEVELOPMENT, 140, 23, p4647-p4656 | en_US |
dc.identifier.issn | 0950-1991 | - |
dc.identifier.uri | http://dev.biologists.org/content/140/23/4647.short | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/45770 | - |
dc.description.abstract | Stem cells and their progenitors are maintained within a microenvironment, termed the niche, through local cell-cell communication. Systemic signals originating outside the niche also affect stem cell and progenitor behavior. This review summarizes studies that pertain to nutritional effects on stem and progenitor cell maintenance and proliferation in Drosophila. Multiple tissue types are discussed that utilize the insulin-related signaling pathway to convey nutritional information either directly to these progenitors or via other cell types within the niche. The concept of systemic control of these cell types is not limited to Drosophila and may be functional in vertebrate systems, including mammals. | en_US |
dc.description.sponsorship | U.B. is supported by the National Institutes of Health and by the UCLA Broad Stem Cell Research Center (BSCRC). J.S. is supported by a California Institute for Regenerative Medicine (CIRM) postdoctoral training grant and by a training grant from the BSCRC. Deposited in PMC for release after 12 months. | en_US |
dc.language.iso | en | en_US |
dc.publisher | COMPANY OF BIOLOGISTS LTD | en_US |
dc.subject | Drosophila | en_US |
dc.subject | Insulin | en_US |
dc.subject | Dilp | en_US |
dc.subject | Germline stem cell | en_US |
dc.subject | Intestinal stem cell | en_US |
dc.subject | Hematopoietic progenitor cell | en_US |
dc.subject | Neural stem cell | en_US |
dc.subject | Amino acid sensing | en_US |
dc.subject | Nutritional control | en_US |
dc.title | Nutritional regulation of stem and progenitor cells in Drosophila | en_US |
dc.type | Article | en_US |
dc.relation.no | 23 | - |
dc.relation.volume | 140 | - |
dc.identifier.doi | 10.1242/dev.079087 | - |
dc.relation.page | 4647-4656 | - |
dc.relation.journal | DEVELOPMENT | - |
dc.contributor.googleauthor | Shim, Jiwon | - |
dc.contributor.googleauthor | Gururaja-Rao, Shubha | - |
dc.contributor.googleauthor | Banerjee, Utpal | - |
dc.relation.code | 2013009669 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF NATURAL SCIENCES[S] | - |
dc.sector.department | DEPARTMENT OF LIFE SCIENCE | - |
dc.identifier.pid | jshim | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.