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Prognostic value of Waldeyer's ring involvement of diffuse large B-cell lymphoma treated with R-CHOP.

Title
Prognostic value of Waldeyer's ring involvement of diffuse large B-cell lymphoma treated with R-CHOP.
Author
송무곤
Keywords
Lymphoma; Large B-cell; Diffuse; Tumor burden
Issue Date
2013-05
Publisher
Springer
Citation
International Journal of Hematology, Mar 2013, 97(3), P.397-402
Abstract
The objective of present study was to compare the prognosis of diffuse large B-cell lymphoma (DLBCL) with Waldeyer's ring involvement (WR-DLBCL) to that of nodal DLBCL (N-DLBCL) without WR involvement. Between July 2004 and October 2009, medical records and metabolic tumor volume (MTV) measured by 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (F-18-FDG) positron emission tomography /computed tomography were collected from patients confirmed with DLBCL. All patients received six or eight cycles of R-CHOP therapy. One hundred and eight patients were included and categorized into WR-DLBCL and N-DLBCL groups. WR involvement and other prognostic factors were analyzed for survivals. High international prognostic index score and high MTV were independent poor prognostic factors. However, WR involvement was a good prognostic factor only in univariate analysis. This study suggests that tumor burden appeared to be more important than specific organ involvement for the prognosis of DLBCL.
URI
http://apps.webofknowledge.com/InboundService.do?customersID=LinksAMR&mode=FullRecord&IsProductCode=Yes&product=WOS&Init=Yes&Func=Frame&DestFail=http%3A%2F%2Fwww.webofknowledge.com&action=retrieve&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&SID=D3avNMo4kHPc6xOFiRW&UT=WOS%3A000316347600013http://hdl.handle.net/20.500.11754/45268
ISSN
0925-5710
DOI
10.1007/s12185-013-1282-3
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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