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Anxiety and depression propensities in patients with acute toxic liver injury

Title
Anxiety and depression propensities in patients with acute toxic liver injury
Author
김태엽
Keywords
Liver injury; Herb; Toxic; Anxiety; Depression; PSYCHOMETRIC PROPERTIES; INVENTORY; DISEASE; DISORDERS; MEDICINE; COMPLEMENTARY; BURDEN; KOREA; COPD
Issue Date
2013-12
Publisher
BAISHIDENG PUBLISHING GROUP INC, 8226 REGENCY DR, PLEASANTON, CA 94588 USA
Citation
World Journal of Gastroenterology, Vol.19, No.47 [2013], p9069-9076
Abstract
AIM: To investigate anxiety and depression propensities in patients with toxic liver injury.METHODS: The subjects were divided into three groups: a healthy control group (Group 1, n = 125), an acute non-toxic liver injury group (Group 2, n = 124), and a group with acute toxic liver injury group caused by non-commercial herbal preparations (Group 3, n = 126). These three groups were compared and evaluated through questionnaire surveys and using the Hospital Anxiety-Depression Scale (HADS), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), and the hypochondriasis scale.RESULTS: The HADS anxiety subscale was 4.9 +/- 2.7, 5.0 +/- 3.0 and 5.6 +/- 3.4, in Groups 1, 2, and 3, respectively. The HADS depression subscale in Group 3 showed the most significant score (5.2 +/- 3.2, 6.4 +/- 3.4 and 7.2 +/- 3.4 in Groups 1, 2, and 3, respectively) (P < 0.01 vs Group 1, P < 0.05 vs Group 2). The BAI and BDI in Group 3 showed the most significant score (7.0 +/- 6.3 and 6.9 +/- 6.9, 9.5 +/- 8.6 and 8.8 +/- 7.3, 10.7 +/- 7.2 and 11.6 +/- 8.5 in Groups 1, 2, and 3, respectively) (BAI: P < 0.01 vs Group 1, P < 0.05 vs Group 2) (BDI: P < 0.01 vs Group 1 and 2). Group 3 showed a significantly higher hypochondriasis score (8.2 +/- 6.0, 11.6 +/- 7.5 and 13.1 +/- 6.5 in Groups 1, 2, and 3, respectively) (P < 0.01 vs Group 1, P < 0.05 vs Group 2).CONCLUSION: Psychological factors that present vulnerability to the temptation to use alternative medicines, such as herbs and plant preparations, are important for understanding toxic liver injury. (C) 2013 Baishideng Publishing Group Co., Limited. All rights reserved.
URI
https://www.wjgnet.com/1007-9327/full/v19/i47/9069.htmhttp://hdl.handle.net/20.500.11754/45222
ISSN
1007-9327
DOI
10.3748/wjg.v19.i47.9069
Appears in Collections:
RESEARCH INSTITUTE[S](부설연구소) > ETC
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