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New tools and new biology: Recent miniaturized systems for molecular and cellular biology

Title
New tools and new biology: Recent miniaturized systems for molecular and cellular biology
Author
Jong Wook Hong
Keywords
cellular biology; human-on-a-chip; microfluidics; molecular biology; organ-on-a-chip; worm-on-a-chip
Issue Date
2013-12
Publisher
Springer
Citation
Molecules and cells, 2013, 36(6), P.485-506
Abstract
Recent advances in applied physics and chemistry have led to the development of novel microfluidic systems. Microfluidic systems allow minute amounts of reagents to be processed using mu m-scale channels and offer several advantages over conventional analytical devices for use in biological sciences: faster, more accurate and more reproducible analytical performance, reduced cell and reagent consumption, portability, and integration of functional components in a single chip. In this review, we introduce how microfluidics has been applied to biological sciences. We first present an overview of the fabrication of microfluidic systems and describe the distinct technologies available for biological research. We then present examples of microsystems used in biological sciences, focusing on applications in molecular and cellular biology.
URI
https://link.springer.com/article/10.1007/s10059-013-0333-1http://hdl.handle.net/20.500.11754/45132
ISSN
1016-8478
DOI
10.1007/s10059-013-0333-1
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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