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Current understanding of dendritic cells in atherosclerosis

Title
Current understanding of dendritic cells in atherosclerosis
Author
최재훈
Keywords
Dendritic Cells; Blood Vessels; Inflammation; Atherosclerosis
Issue Date
2013-02
Publisher
Hanyang University College of Medicine
Citation
Hanyang Med Rev , 52-58
Abstract
Dendritic cells (DCs), first identified in 1973, have been shown to be the principal cells involved in antigen presentation to T cells, and are more potent in the presentation of antigen than B cells or macrophages. Atherosclerosis is a representative chronic vascular inflammatory disease in which various immune cells have been implicated in the formation of atherosclerotic plaque. Thus, the quantification and elucidation of activity of immune populations in atherosclerotic vessels are very important in understanding the pathogenesis of atherosclerosis. Several current studies demonstrate that DCs which exist in atherosclerotic lesion appear to play several important roles in atherosclerosis. This review summarizes current understandings on the function of DCs in atherosclerosis, and also suggests future directions for research of DC function in inflammatory atherosclerotic vascular disease.
URI
https://synapse.koreamed.org/DOIx.php?id=10.7599/hmr.2013.33.1.52http://hdl.handle.net/20.500.11754/44918
ISSN
1738-429X
DOI
10.7599/hmr.2013.33.1.52
Appears in Collections:
COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
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