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dc.contributor.author김순길-
dc.date.accessioned2018-03-11T03:20:41Z-
dc.date.available2018-03-11T03:20:41Z-
dc.date.issued2013-10-
dc.identifier.citationJOURNAL OF INTERVENTIONAL CARDIOLOGY, 2013, 26(5), P.491-500en_US
dc.identifier.issn0896-4327-
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1111/joic.12060/full-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/44893-
dc.description.abstractBackgroundCoronary vasospasm causes variant angina, as well as acute myocardial infarction, ventricular tachycardia, and sudden cardiac death. We evaluated morphological changes due to vasospastic lesions, which may cause acute coronary syndrome (ACS), using a novel technique called optical coherence tomography (OCT).MethodsTwenty patients (40-83 years old, 19 males) with vasospasm-induced ACS who visited the emergency room because of continuous chest pain and displayed transient ST segment elevation in their electrocardiogram were enrolled in the study. None of these patients had significant coronary artery disease and all had positive results in the provocation test. OCT examinations were performed for evaluation of vasospastic lesions.ResultsIntraluminal thrombi and intimal erosion were found in 6 (33.3%) and 2 patients (10%), respectively. High-sensitivity C-reactive protein levels were significantly higher in patients with microthrombi (2.663.33mg/L) compared with those in patients without microthrombi (0.49 +/- 0.30mg/L; P=0.022). Serum cardiac troponin-I levels were not significantly different between patients with or without microthrombi (2.37 +/- 5.31ng/mL vs. 1.45 +/- 4.68ng/mL; P=0.704). Other parameters, including creatinine kinase-myocardial band isoenzyme, total cholesterol, pain duration, residual stenosis, lesion length, and coronary risk factors, were not significantly different between the 2 groups.ConclusionIn patients with vasospasm-induced ACS, microthrombi with or without intimal erosion are major abnormal morphologic findings of OCT examinations. However, further large-scale studies are required for validation. (J Interven Cardiol 2013;26:491-500)en_US
dc.language.isoenen_US
dc.publisherWILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USAen_US
dc.subjectMYOCARDIAL-INFARCTIONen_US
dc.subjectINTRAVASCULAR ULTRASOUNDen_US
dc.subjectARTERIAL SPASMen_US
dc.subjectATHEROSCLEROTIC PLAQUEen_US
dc.subjectVASOSPASTIC ANGINAen_US
dc.subjectDEATHen_US
dc.subjectPATHOGENESISen_US
dc.subjectFEATURESen_US
dc.subjectRUPTUREen_US
dc.subjectTHROMBIen_US
dc.titleMorphological Findings in Typical Variant Angina Presenting as Acute Coronary Syndrome Using Optical Coherence Tomographyen_US
dc.typeArticleen_US
dc.relation.volume26-
dc.identifier.doi10.1111/joic.12060-
dc.relation.page491-500-
dc.relation.journalJOURNAL OF INTERVENTIONAL CARDIOLOGY-
dc.contributor.googleauthorPark, Hwan-Cheol-
dc.contributor.googleauthorChoi, Sung Il-
dc.contributor.googleauthorLee, Jae Ung-
dc.contributor.googleauthorKim, Soon-Gil-
dc.contributor.googleauthorShin, Jinho-
dc.contributor.googleauthorKim, Hyun-Joong-
dc.relation.code2013004971-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidkimsg-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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