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Microtools for single-cell analysis in biopharmaceutical development and manufacturing

Title
Microtools for single-cell analysis in biopharmaceutical development and manufacturing
Author
최종훈
Keywords
microtools; biologic; microengraving; microwells
Issue Date
2013-05
Publisher
Elsevier Science London
Citation
Trends in Biotechnology Oxford, May 2013, 31(5), P.280-286.
Abstract
Biologic drugs are promoting growth in the biopharmaceutical industry. Despite the clinical benefits of these drugs, the time and costs required to bring new biologics to market still are substantial. Three key challenges, among others, persist in the development of biologic drugs: namely, establishing product similarity, product toxicity, and global accessibility. New classes of microtools that facilitate the isolation and interrogation of single cells have the potential to impact each of these challenges. This opinion considers recent examples of microtools with demonstrated or potential utility to address problems in these areas. Integrating these advanced technologies into the development of new biologics could greatly reduce time and costs required to bring alternative products to market, and thus expand their global availability.
URI
http://search.proquest.com/docview/1645139612/fulltextPDF/21739104C4A34440PQ/1?accountid=11283http://hdl.handle.net/20.500.11754/44511
ISSN
0167-7799
DOI
10.1016/j.tibtech.2013.03.001
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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