Dual-energy CT to detect recurrent HCC after TACE: Initial experience of color-coded iodine CT imaging
- Title
- Dual-energy CT to detect recurrent HCC after TACE: Initial experience of color-coded iodine CT imaging
- Author
- 박충기
- Keywords
- Dual-energy CT; Iodine map; Hepatocellular carcinoma; Transcatheter arterial chemoembolization (TACE); Recurrence; Diagnostic performance
- Issue Date
- 2013-04
- Publisher
- Elsevier Science B.V., Amsterdam.
- Citation
- European journal of radiology, 2013, 82(4), P.569-576
- Abstract
- Objectives: To evaluate the feasibility of diagnosing recurrence of HCC after TACE color-coded iodine CT (CICT) based on arterial phase scans obtained by a dual-energy CT (DECT) scanner. Methods: A CICT scan was acquired from an iodine map after applying material decomposition of the liver tissue and setting a threshold attenuation level for viable tumors. Two radiologists reviewed both conventional and CICT sets in 31 patients who had a history of TACE for HCC. The performances in detecting local tumor progression (LTP) were evaluated by alternative free-response receiver operating characteristics. The rate of uncertain diagnosis and interobserver agreement of the diagnosis were explored. Additionally, the reading time and radiation dose were also investigated. Results: The mean figures of merit of the conventional and CICT sets for LTP were 0.818 and 0.847, respectively (p = 0.459). The rate of uncertain diagnosis was significantly decreased in CICT sets (34.5% vs. 0%), and interobserver agreement was improved (k = 0.527 vs. 0.718). On the CICT set, mean reading time was reduced by 49 s and mean radiation dose was also decreased by 18.3% when replacing the non-contrast CT with CICT. Conclusions: CICT is comparable to conventional liver CT protocol in demonstrating viable HCCs, while it allows a reduction in radiation dose. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
- URI
- https://www.sciencedirect.com/science/article/pii/S0720048X12005591http://hdl.handle.net/20.500.11754/43996
- ISSN
- 0720-048X
- DOI
- 10.1016/j.ejrad.2012.11.014
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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