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근거중심 한국형 우울증 약물학적 치료지침, 개정판(I) : 항우울제 치료의 초기선택

Title
근거중심 한국형 우울증 약물학적 치료지침, 개정판(I) : 항우울제 치료의 초기선택
Other Titles
Evidence-Based Korean Pharmacological Treatment Guideline for Depression, Revised Edition (I) : Initial Choice of Antidepressant Treatment
Author
최준호
Keywords
ZDepression; Pharmacological treatment; Antidepressant; Initial choice; Korean
Issue Date
2013-07
Publisher
대한신경정신의학회(THE KOREAN NEUROPSYCHIATRIC ASSOCIATION)
Citation
神經精神醫學(JOURNAL OF THE KOREAN NEUROPSYCHIATRIC ASSOCIATION),Vol.52 No.4 [2013],p253-262
Abstract
Objectives The aim of this study is to establish Korean pharmacological treatment guidelines for the initial choice of antidepressant for treatment of moderate or severe depression.Methods The process for establishment of guidelines involved determination of important key questions, selection of 12 international and domestic clinical practice guidelines for depression,drawing of recommendation drafts, and peer review.Results Selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), norepinephrine-dopamine reuptake inhibitors (NDRI), and noradrenergic and specific serotonergic antidepressants (NaSSA) were strongly recommended as the first?line antidepressants for treatment of moderate or severe depression. SSRIs were weakly recommended for patients who had problems with tolerability. Consideration of not only efficacy but also provisional adverse effects, drug-drug interactions, history of treatment response, preference, acceptability, cost, comorbid illnesses, and other factors in the choice of first-line antidepressants was strongly recommended. The treatment recommendations for specific clinical features of depression were as follows. SSRIs were weakly recommended for atypical depression. Augmented use of antipsychotics to antidepressants was strongly recommended for psychotic depression. Bupropion and SSRIs were weakly recommended for seasonal depression.Conclusion The results of this study may contribute toward improving the quality of depression treatment by providing clear and definite recommendations for the initial choice of antidepressant for treatment of moderate or severe depression.
URI
https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001792130http://hdl.handle.net/20.500.11754/43969
ISSN
1015-4817
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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