Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 황승용 | - |
dc.date.accessioned | 2018-03-05T04:19:28Z | - |
dc.date.available | 2018-03-05T04:19:28Z | - |
dc.date.issued | 2011-03 | - |
dc.identifier.citation | MOLECULAR AND CELLULAR TOXICOLOGY,Vol.7 No.1 [2011],95-101 | en_US |
dc.identifier.issn | 1738-642X | - |
dc.identifier.uri | https://link.springer.com/article/10.1007%2Fs13273-011-0013-1 | - |
dc.description.abstract | Exposure to environmental chemicals has been implicated in a number of adverse health effects, including immunotoxic, neurotoxic, reproductive toxic effects, and, above all, cancers. In the present study, we investigated toxicity of three environmental chemicals-bisphenol A (BPA), nonylphenol (NP), and tetrabutyltin (TTBT) in a human breast cancer cell line by HazChem Human array. We then found toxicity markers of TTBT through comparison with BPA and NP. Fifty three genes were differentially expressed and seventeen genes showed similar expression patterns. Ontology analysis showed differential expression of genes related to aging and apoptosis and genes having similarities associated with pregnancy and insemination. In this paper, we revealed potential TTBT toxic markers and endotoxicity of TTBT. This study could be a foundation for additional studies of TIBT toxicity. | en_US |
dc.description.sponsorship | This subject is supported by the Korea Ministry of Environment as a "Converging technology project" and this work was supported by the Ministry of Environment with an Eco-Technopia 21 Project grant through the Development of Decision System by Toxic Substances at the Korea Institute of Toxicology. | en_US |
dc.language.iso | en | en_US |
dc.publisher | KOREAN SOCIETY TOXICOGENOMICS & TOXICOPROTEOMICS-KSTT, HANYANG UNIV, SCI & TECHNOL BLDG 1, RM 423, SA-DONG, SANGROK-GU, ANSAN, GYEONGGI-DO, 426 791, SOUTH KOREA | en_US |
dc.subject | Tetrabutyltin | en_US |
dc.subject | HazChem Human array | en_US |
dc.subject | Toxicity | en_US |
dc.subject | Endotoxic | en_US |
dc.subject | NONYLPHENOL | en_US |
dc.subject | ENVIRONMENT | en_US |
dc.title | Analysis of toxicity of tetrabutyltin: comparing with EDC chemicals | en_US |
dc.type | Article | en_US |
dc.relation.no | 1 | - |
dc.relation.volume | 7 | - |
dc.identifier.doi | 10.1007/s13273-011-0013-1 | - |
dc.relation.page | 95-101 | - |
dc.relation.journal | MOLECULAR & CELLULAR TOXICOLOGY | - |
dc.contributor.googleauthor | An, Y. R. | - |
dc.contributor.googleauthor | Kim, S. J. | - |
dc.contributor.googleauthor | Park, H. W. | - |
dc.contributor.googleauthor | Yu, S. Y. | - |
dc.contributor.googleauthor | Han, J. | - |
dc.contributor.googleauthor | Oh, J. H. | - |
dc.contributor.googleauthor | Yoon, S. J | - |
dc.contributor.googleauthor | Hwang, S. Y. | - |
dc.relation.code | 2011215780 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | syhwang | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.