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dc.contributor.author황승용-
dc.date.accessioned2018-03-05T04:19:28Z-
dc.date.available2018-03-05T04:19:28Z-
dc.date.issued2011-03-
dc.identifier.citationMOLECULAR AND CELLULAR TOXICOLOGY,Vol.7 No.1 [2011],95-101en_US
dc.identifier.issn1738-642X-
dc.identifier.urihttps://link.springer.com/article/10.1007%2Fs13273-011-0013-1-
dc.description.abstractExposure to environmental chemicals has been implicated in a number of adverse health effects, including immunotoxic, neurotoxic, reproductive toxic effects, and, above all, cancers. In the present study, we investigated toxicity of three environmental chemicals-bisphenol A (BPA), nonylphenol (NP), and tetrabutyltin (TTBT) in a human breast cancer cell line by HazChem Human array. We then found toxicity markers of TTBT through comparison with BPA and NP. Fifty three genes were differentially expressed and seventeen genes showed similar expression patterns. Ontology analysis showed differential expression of genes related to aging and apoptosis and genes having similarities associated with pregnancy and insemination. In this paper, we revealed potential TTBT toxic markers and endotoxicity of TTBT. This study could be a foundation for additional studies of TIBT toxicity.en_US
dc.description.sponsorshipThis subject is supported by the Korea Ministry of Environment as a "Converging technology project" and this work was supported by the Ministry of Environment with an Eco-Technopia 21 Project grant through the Development of Decision System by Toxic Substances at the Korea Institute of Toxicology.en_US
dc.language.isoenen_US
dc.publisherKOREAN SOCIETY TOXICOGENOMICS & TOXICOPROTEOMICS-KSTT, HANYANG UNIV, SCI & TECHNOL BLDG 1, RM 423, SA-DONG, SANGROK-GU, ANSAN, GYEONGGI-DO, 426 791, SOUTH KOREAen_US
dc.subjectTetrabutyltinen_US
dc.subjectHazChem Human arrayen_US
dc.subjectToxicityen_US
dc.subjectEndotoxicen_US
dc.subjectNONYLPHENOLen_US
dc.subjectENVIRONMENTen_US
dc.titleAnalysis of toxicity of tetrabutyltin: comparing with EDC chemicalsen_US
dc.typeArticleen_US
dc.relation.no1-
dc.relation.volume7-
dc.identifier.doi10.1007/s13273-011-0013-1-
dc.relation.page95-101-
dc.relation.journalMOLECULAR & CELLULAR TOXICOLOGY-
dc.contributor.googleauthorAn, Y. R.-
dc.contributor.googleauthorKim, S. J.-
dc.contributor.googleauthorPark, H. W.-
dc.contributor.googleauthorYu, S. Y.-
dc.contributor.googleauthorHan, J.-
dc.contributor.googleauthorOh, J. H.-
dc.contributor.googleauthorYoon, S. J-
dc.contributor.googleauthorHwang, S. Y.-
dc.relation.code2011215780-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidsyhwang-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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