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dc.contributor.author김순길-
dc.date.accessioned2018-02-28T05:18:54Z-
dc.date.available2018-02-28T05:18:54Z-
dc.date.issued2011-05-
dc.identifier.citationKOREAN CIRCULATION JOURNAL MAY 2011, 41 (5), 235-240en_US
dc.identifier.issn1738-5520-
dc.identifier.urihttps://synapse.koreamed.org/DOIx.php?id=10.4070/kcj.2011.41.5.235-
dc.description.abstractBackground and Objectives: Ambulatory arterial stiffness index (AASI) is well known as a predictor of cardiovascular mortality in hypertensive patients. Mathematically, AASI reflect the standard deviation (SD) of blood pressure (BP) variation. AASI is measured higher levels in non-dipper than dipper. Thus, AASI has a possibility of not only reflecting arterial stiffness but also BP variability and/or autonomic nervous dysfunction. Subjects and Methods: Consecutive data from 418 untreated hypertensive patients were analyzed retrospectively. We examined the association between the 24-hour ambulatory BP monitoring (ABPM) parameters and AASI. Results: AASI had a simple correlation with age (R=0.189, p<0.001), relative wall thickness (RWT) (R=0.115, p=0.019), left ventricular mass index (LVMI) (R=0.192, p<0.001), average systolic BP (SBP) (R=0.232, p<0.001), average pulse pressure (PP) (R=0.363, p<0.001), SD of diastolic BP (DBP) (R=-0.352,p<0.001), SD of PP (R=0.330, p<0.001), SD of heart rate (HR) (R=-0.268, p<0.001), and nocturnal dipping (R=-0.137, p=0.005). In multiple linear regression analysis model including clinical parameters and 24 hour-ABPM parameters, independent predictors of AASI were SD of PP (beta=1.246, p<0.001), SD of DBP (beta=-1.067, p<0.001), SD of SBP (beta=-0.197, p<0.001), and non-dipper (beta=0.054, p=0.033). Conclusion: AASI is closely correlated with BP variability. The result of this study shows that AASI is not only a parameter for arterial stiffness, but also a parameter for BP variability.en_US
dc.language.isoenen_US
dc.publisherKOREAN SOC CARDIOLOGYen_US
dc.subjectBlood pressureen_US
dc.subjectBlood pressure monitoring, ambulatoryen_US
dc.subjectAutonomic nervous system diseasesen_US
dc.titleThe relation between ambulatory arterial stiffness index and blood pressure variability in hypertensive patientsen_US
dc.typeArticleen_US
dc.relation.no5-
dc.relation.volume41-
dc.identifier.doi10.4070/kcj.2011.41.5.235-
dc.relation.page235-240-
dc.relation.journalKorean Circulation Journal-
dc.contributor.googleauthorLee, Hyung Tak-
dc.contributor.googleauthorLim, Young-Hyo-
dc.contributor.googleauthorKim, Bae Keun-
dc.contributor.googleauthorLee, Kang Won-
dc.contributor.googleauthorLee, Jae Ung-
dc.contributor.googleauthorKim, Kyung Soo-
dc.contributor.googleauthorKim, Soon Gil-
dc.contributor.googleauthorKim, Jeong Hyun-
dc.contributor.googleauthorLim, Heon Kil-
dc.contributor.googleauthorShin, Jinho-
dc.relation.code2012231755-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidkimsg-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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