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점액양 변성을 동반한 CD34 양성 사구종양 2예

Title
점액양 변성을 동반한 CD34 양성 사구종양 2예
Other Titles
Two Cases of CD34-positive Glomus Tumors with Myxoid Stromal Changes
Author
김정수
Keywords
CD34; Glomus tumor; Myxoid
Issue Date
2012-11
Publisher
대한피부과학회
Citation
대한피부과학회지, 권: 50, 호: 11, 페이지: 969-973
Abstract
Glomus tumors are benign cutaneous neoplasm, occurring in the vascular hamartomatous tubercles of the glomus body, which is a myoarterial apparatus typically found in the reticular dermis of the skin. Histopathologically,glomus tumors are composed of neoplastic cells that resemble normal glomus cells, arranged around a varying number of thin-walled, sometimes branching capillaries. Immunohistochemically, neoplastic cells in glomus tumors clearly exhibit smooth muscle characteristics with expression of muscle-specific actin and α-smooth muscle actin;whereas, the expression of CD34 is rare. In this report, we present two cases of benign glomus tumors on the subungual area and palm. Tumor cells of glomus tumor in two patients were both positive for smooth muscle actin (SMA) and CD34 immunohistochemical staining. We thought that coexpression of SMA and CD34 adds support to the interpretation of these lesions as a family of perivascular neoplasms.
URI
http://kiss.kstudy.com/thesis/thesis-view.asp?key=3125579http://hdl.handle.net/20.500.11754/38082
ISSN
0494-4739
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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