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dc.contributor.author유혜현-
dc.date.accessioned2018-02-19T02:33:10Z-
dc.date.available2018-02-19T02:33:10Z-
dc.date.issued2015-08-
dc.identifier.citationTRIALS, v. 16, Page. 327en_US
dc.identifier.issn1745-6215-
dc.identifier.urihttps://trialsjournal.biomedcentral.com/articles/10.1186/s13063-015-0867-y-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/38054-
dc.description.abstractBackground: Complex metabolic changes cause obesity, making weight loss difficult. For this reason, understanding metabolism is important, and considering the shortcomings of conventional treatment options for obesity, acupuncture is a possible option. However, evidence supporting its efficacy on metabolic parameters in obese patients is lacking. The aim of this study is to investigate the effects of acupuncture on serum metabolic parameters in premenopausal obese women. Methods/design: This ongoing study is a randomized, patient-assessor blind, two-arm parallel non-penetrating sham-controlled clinical trial. Eligible participants, premenopausal adult women (19 years of age or older) with a clinical diagnosis of obesity (body mass index of 25 kg/m(2) or more) blinded to the treatment received, will be randomly allocated blindly into the real acupuncture treatment group (manual acupuncture plus electroacupuncture, n = 60) or the sham acupuncture control group (sham acupuncture plus placebo acupuncture without electrical stimulation, n = 60) and receive treatment two times a week for a total of 12 sessions over 6 weeks. The primary outcome measure is the serum cholesterol and triglyceride (TG) levels at baseline and endpoint. The secondary outcomes are body weight, body fat mass, muscle mass, waist and hip circumference, other serum metabolic profiles, International Physical Activity Questionnaire (IPAQ), Social Readjustment Rating Scale (SRRS), Stress Response Inventory (SRI), Fatigue Severity Scale (FSS), the Korean version of the Beck Depression Inventory (BDI), and urine metabolites. Adverse events will be assessed at every visit. Discussion: The results of this trial (which will be available in 2015) will provide important clinical evidence for the effect of acupuncture on serum metabolites and demonstrate how acupuncture can be helpful for the treatment of obesity.en_US
dc.description.sponsorshipThis research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (number 2005-0049404) and a grant from the Korean Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea (HI13C0540).en_US
dc.language.isoen_USen_US
dc.publisherBIOMED CENTRAL LTDen_US
dc.subjectObesityen_US
dc.subjectAcupunctureen_US
dc.subjectMetabolomicsen_US
dc.subjectEffecten_US
dc.subjectSafetyen_US
dc.subjectClinical research protocolen_US
dc.subjectPHYSICAL-ACTIVITY QUESTIONNAIREen_US
dc.subjectFATIGUE SEVERITY SCALEen_US
dc.subjectBODY-MASS INDEXen_US
dc.subjectMETAANALYSISen_US
dc.subjectOVERWEIGHTen_US
dc.subjectVALIDITYen_US
dc.subjectCANCERen_US
dc.subjectCOHORTen_US
dc.titleEffects of acupuncture on serum metabolic parameters in premenopausal obese women: study protocol for a randomized controlled trialen_US
dc.typeArticleen_US
dc.relation.volume16-
dc.identifier.doi10.1186/s13063-015-0867-y-
dc.relation.page327-327-
dc.relation.journalTRIALS-
dc.contributor.googleauthorKim, KW-
dc.contributor.googleauthorYoo, HH-
dc.contributor.googleauthorCho, JH-
dc.contributor.googleauthorYang, YC-
dc.contributor.googleauthorKim, JI-
dc.contributor.googleauthorKim, SY-
dc.contributor.googleauthorPark, JY-
dc.contributor.googleauthorPark, HJ-
dc.contributor.googleauthorSong, MY-
dc.relation.code2015010927-
dc.sector.campusE-
dc.sector.daehakCOLLEGE OF PHARMACY[E]-
dc.sector.departmentDEPARTMENT OF PHARMACY-
dc.identifier.pidyoohh-
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COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
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