65 0

Prognostic Factors for Gastric Cancer Patients with Synchronous Metastasis

Title
Prognostic Factors for Gastric Cancer Patients with Synchronous Metastasis
Author
하태경
Keywords
Gastric cancer; Metastasis; Prognostic factors
Issue Date
2011-05
Publisher
대한외과학회
Citation
Journal of the Korean Surgical Society, Volume 80, Issue 1, Pages 16-22
Abstract
The prognosis for gastric cancer patients with distant metastasis is very poor. The purpose of this study was to evaluate the prognosis and survival for gastric cancer patients with synchronous metastasis. Methods: Among 2,083 gastric cancer patients who received surgery at the Department of Surgery, Hanyang University Hospital from 1992 to 2009, 164 patients revealed distant metastasis. However, 3 patients who died of postoperative complications were excluded. For the remaining patients, various clinicopathological factors were analyzed using univariate and multivariate survival analyses. Results: Systemic chemotherapy (SC), type of surgery, lymph node dissection, degree of peritoneal carcinomatosis (PC), presence of ascites and tumor location were significant prognostic factors. However, sex, age, number of metastatic sites and histologic classification were not significant prognostic factors. In multivariate analysis, the type of surgery, the SC and the degree of PC were independent prognostic factors. Survival benefit by SC was significant in single site metastasis. The significant survival difference between resection and non-resection groups was observed regardless of number of metastatic sites. Conclusion: In gastric cancer patients with metastasis, the favorable prognostic factors were type of surgery and SC in single metastasis. The gastrectomy improves the prognosis regardless of number of metastatic sites. However, a prospective randomized clinical trial is mandatory to attain more accurate information.
URI
https://synapse.koreamed.org/DOIx.php?id=10.4174/jkss.2011.80.1.16
ISSN
1226-0053; 2093-0488
DOI
10.4174/jkss.2011.80.1.16
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE