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Protective effects of cleavage agents on INS-1 cells against h-IAPP-induced apoptosis

Title
Protective effects of cleavage agents on INS-1 cells against h-IAPP-induced apoptosis
Author
채필석
Issue Date
2012-01
Publisher
ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Citation
CHEMICAL COMMUNICATIONS, 권: 48, 호: 4, 페이지: 588-590
Abstract
Cleavage agents showed cleavage yields as much as 9-14%, which does not sufficiently support the agents' protection of beta-cells from the cytotoxicity of h-IAPP. INS-1 cell tests were carried out to better understand the potential of using these cleavage agents as drug candidates. This study provides the firm basis for clinical applicability of these cleavage agents.
URI
http://pubs.rsc.org/en/Content/ArticleLanding/2012/CC/C1CC16293D#!divAbstracthttp://hdl.handle.net/20.500.11754/37520
ISSN
1359-7345
DOI
10.1039/c1cc16293d
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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