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dc.contributor.author이민형-
dc.date.accessioned2018-02-14T05:47:44Z-
dc.date.available2018-02-14T05:47:44Z-
dc.date.issued2011-11-
dc.identifier.citationJournal of Controlled Release. Nov 2011, 152 Suppl 1: P.146-148en_US
dc.identifier.issn0168-3659-
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S0168365911006675?via%3Dihub-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/37445-
dc.description.abstractSUMMARY: For glia/hypoxia dual specific gene expression, a dual specific expression vector was developed. pEpo-NI2-SV-Luc or pEpo-NI2-SV-was constructed with the nestin intron 2 (NI2)-SV40 promoter and erythropoietin (Epo) enhancer for glia cell and hypoxia specific gene expression. Gene expression by pEpo-NI2-SV-Luc was higher than pSV-Luc in glioblastoma cells under hypoxia. pEpo-NI2-SV-TK was constructed and transfected into C6 cells. The growth of the pEpo-NI2-SV-TK transfected cells was significantly suppressed in the presence of GCV.en_US
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.subjectGene regulationen_US
dc.subjectHypoxiaen_US
dc.subjectGlioblastomaen_US
dc.subjectGene therapyen_US
dc.titleGlia/ischemia tissue dual specific gene expression vector for glioblastoma gene therapyen_US
dc.title.alternativeischemia tissue dual specific gene expression vector for glioblastoma gene therapyen_US
dc.typeArticleen_US
dc.relation.volume152-
dc.identifier.doi10.1016/j.jconrel.2011.08.053-
dc.relation.page146-148-
dc.relation.journalJOURNAL OF CONTROLLED RELEASE-
dc.contributor.googleauthorKim, Hyun Ah-
dc.contributor.googleauthorPark, Ji Hwan-
dc.contributor.googleauthorCho, Su Hee-
dc.contributor.googleauthorLee, Jiyoung-
dc.contributor.googleauthorLee, Minhyung-
dc.contributor.googleauthor김현아-
dc.contributor.googleauthor박지환-
dc.contributor.googleauthor조수희-
dc.contributor.googleauthor이지영-
dc.contributor.googleauthor이민형-
dc.relation.code2011204927-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF ENGINEERING[S]-
dc.sector.departmentDEPARTMENT OF BIOENGINEERING-
dc.identifier.pidminhyung-
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COLLEGE OF ENGINEERING[S](공과대학) > BIOENGINEERING(생명공학과) > Articles
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