F-18 flluorodeoxyglucose positron emission tomography and computed tomography is not accurate in preoperative staging of gastric cancer
- Title
- F-18 flluorodeoxyglucose positron emission tomography and computed tomography is not accurate in preoperative staging of gastric cancer
- Author
- 최윤영
- Keywords
- Gastric cancer; 18F-FDG-PET/CT; MDCT; Preoperative staging
- Issue Date
- 2011-08
- Publisher
- 대한외과학회
- Citation
- 대한외과학회지,82(2),104-110
- Abstract
- Purpose: To investigate the clinical benefits of F18-fluorodeoxyglucose-positron emission tomography and computed tomography (18F-FDG-PET/CT) over multi-detector row CT (MDCT) in preoperative staging of gastric cancer. Methods: FDG-PET/CT and MDCT were performed on 78 patients with gastric cancer pathologically diagnosed by endoscopy. The accuracy of radiologic staging retrospectively was compared to pathologic result after curative resection. Results: Primary tumors were detected in 51 (65.4%) patients with 18F-FDG-PET/CT, and 47 (60.3%) patients with MDCT. Regarding detection of lymph node metastasis, the sensitivity of FDG-PET/CT was 51.5% with an accuracy of 71.8%, whereas those of MDCT were 69.7% and 69.2%, respectively. The sensitivity of 18F-FDG-PET/CT for a primary tumor with signet ring cell carcinoma was lower than that of 18F-FDG-PET/CT for a primary tumor with non-signet ring cell carcinoma (35.3% vs. 73.8%, P < 0.01). Conclusion: Due to its low sensitivity, 18F-FDG-PET/CT alone shows no definite clinical benefit for prediction of lymph node metastasis in preoperative staging of gastric cancer.
- URI
- https://synapse.koreamed.org/DOIx.php?id=10.4174/jkss.2011.81.2.104
- ISSN
- 1226-0053
- DOI
- 10.4174/jkss.2011.81.2.104
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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