A case of lupus erythematosus panniculitis presenting as combined linear and lipoatrophic skin lesions
- Title
- A case of lupus erythematosus panniculitis presenting as combined linear and lipoatrophic skin lesions
- Author
- 고주연
- Keywords
- Norovirus; Gastroenteritis; Disease Outbreaks; Contaminated Groundwater; DNA Sequencing
- Issue Date
- 2011-03
- Publisher
- WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
- Citation
- INTERNATIONAL JOURNAL OF DERMATOLOGY 권: 50 호: 2 페이지: 203-205
- Abstract
- In January 2008, an outbreak of acute gastroenteritis at a waterpark was reported to the Bundang-gu Public Health Center in Seongnam, Korea. To determine the etiological agent and mode of transmission, a retrospective cohort study was done using structured questionnaires and stool samples from patients who had current gastrointestinal symptoms and three food handlers were tested. A total of 67 (31.0%) students and teachers developed acute gastroenteritis. No food items were associated with an increased risk of the illness. Norovirus was detected in 3 stool specimens collected from 6 patients who had severe diarrhea using semi-nested RT-PCR. All the specimens contained the genogroup I strains of the norovirus. Norovirus was also detected in the groundwater samples from the waterpark. In the nucleotide sequencing analysis, all the genogroup I noroviruses from the patients and groundwater samples were identified as the norovirus genotype 1-4 strain. They were indistinguishable by DNA sequencing with a 97% homology. We conclude the outbreak of acute gastroenteritis caused by the norovirus was closely related to the contaminated groundwater.
- URI
- http://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-4632.2009.04457.x
- ISSN
- 0011-9059; 1365-4632
- DOI
- 10.1111/j.1365-4632.2010.04457.x
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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