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Non-dipper pattern is a determinant of the inappropriateness of left ventricular mass in essential hypertensive patients

Title
Non-dipper pattern is a determinant of the inappropriateness of left ventricular mass in essential hypertensive patients
Author
김순길
Keywords
Hypertension; Hypertrophy; left ventricular; Blood pressure monitoring; ambulatory
Issue Date
2011-04
Publisher
Korean SOC Cardiology
Citation
Korean Circulation Journal, 2011, 41(4), P.191-197
Abstract
Background and Objectives: Inappropriately high left ventricular mass (iLVM) is known to be related to cardiovascular prognosis. A non-dipper pattern has a greater mean left ventricular (LV) mass than the dipper pattern in hypertensive patients. However, the appropriateness of LV mass in dipper or non-dipper patterns has not been adequately investigated. The aim of this study was to define the relationship between nocturnal dipping and the appropriateness of LV mass. Subjects and Methods: Using the ambulatory blood pressure monitoring (ABPM) database, the data of 361 patients who underwent ABPM and echocardiography was analyzed retrospectively. Appropriateness of LV mass was calculated as observed/predicted ratio of LV mass (OPR) using a Korean-specified equation. Nocturnal dipping was expressed as percent fall in systolic blood pressure (BP) during the night compared to the day. Results: Daytime, nighttime and 24 hours BP in hypertensive patients was 140.4 +/- 14.8 mmHg, 143.7 +/- 15.2 mmHg and 129.4 +/- 20.0 mmHg, respectively. OPR was 106.3 +/- 19.9% and nocturnal dipping was 10.2 +/- 10.9 mmHg. In a multiple linear regression model, 24 hours systolic BP (beta=0.097, p=0.043) and nocturnal dipping (beta=-0.098, p=0.046) were independent determinants of OPR as well as age (beta=0.130, p=0.025) and body mass index (BMI) (beta=0.363, p<0.001). Odds ratio of the non-dipper pattern was 2.134 for iLVM (p=0.021) and 3.694 for obesity (p<0.001; BMI >25 kg/m(2)). Conclusion: The non-dipper pattern is independently associated with iLVM in hypertensive patients as well as obesity.
URI
https://synapse.koreamed.org/DOIx.php?id=10.4070/kcj.2011.41.4.191
ISSN
1738-5520; 1738-5555
DOI
10.4070/kcj.2011.41.4.191
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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