Immunosensing of Atrazine with Antibody-Functionalized Cu-MOF Conducting Thin Films
- Title
- Immunosensing of Atrazine with Antibody-Functionalized Cu-MOF Conducting Thin Films
- Author
- 김기현
- Keywords
- MOF; conducting; thin films; sensor; polyaniline; atrazine
- Issue Date
- 2015-12
- Publisher
- AMER CHEMICAL SOC
- Citation
- ACS APPLIED MATERIALS & INTERFACES, v. 7, NO 47, Page. 26124-26130
- Abstract
- This work reports the assembly of thin films of a silica (SiO2)-modified copper metal organic framework, Cu-3(BTC)(2) [Cu-3(BTC)(2)@SiO2, BTC = benzene-1,3,5-tricarboxylic acid] on a conducting substrate of NH2-BDC [NH2-BDC = 2-aminobenzene-1,4-dicarboxylic acid] doped polyaniline (PANI). Assembled Cu-3(BTC)(2)@SiO2/BDC-PANI thin films displayed electrical conductivity in the range of 35 mu A. These thin films were conjugated with antiatrazine antibodies to create a novel immunosensing platform. Various structural and spectral characteristics of the synthesized material and its bioconjugate were investigated. The developed immunosensor was used for the conductometric sensing of atrazine. The detection of atrazine was achieved with a high sensor sensitivity (limit of detection = 0.01 nM) and specificity in the presence of diverse pesticides (e.g., endosulfan, parathion, paraoxon, malathion, and monochrotophos).
- URI
- http://pubs.acs.org/doi/10.1021/acsami.5b07692http://hdl.handle.net/20.500.11754/29466
- ISSN
- 1944-8244
- DOI
- 10.1021/acsami.5b07692
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > CIVIL AND ENVIRONMENTAL ENGINEERING(건설환경공학과) > Articles
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