Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김근호 | - |
dc.date.accessioned | 2017-09-06T00:37:23Z | - |
dc.date.available | 2017-09-06T00:37:23Z | - |
dc.date.issued | 2015-11 | - |
dc.identifier.citation | ARTIFICIAL ORGANS, v. 39, NO 11, Page. 965-972 | en_US |
dc.identifier.issn | 0160-564X | - |
dc.identifier.issn | 1525-1594 | - |
dc.identifier.uri | http://onlinelibrary.wiley.com/doi/10.1111/aor.12473/abstract;jsessionid=722CB9777785F12B023F974A22343FCE.f03t03 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/28918 | - |
dc.description.abstract | Hypoalbuminemia is associated with poor outcomes in kidney transplantation (KT). However, what level is optimal in serum albumin is not clear for the long-term prognosis. To determine whether the long-term outcomes are different even between the normal ranges of serum albumin after KT, we analyzed data from 404 renal allograft recipients whose 1-year post-transplant serum albumin levels were within the normal limits (3.5-5.5g/dL). During a follow-up of 122 +/- 56 months, 97 graft losses, 20 patient deaths, and 50 cardiovascular (CV) events occurred. Based on 1-year serum albumin levels, the patients were divided into high normal (4.6g/dL, n=209) and low normal (˂4.6g/dL, n=195) groups. Kaplan-Meier analyses revealed that the low normal group had poorer allograft survival (P=0.01), patient survival (P˂0.001), and CV event-free survival (P˂0.001) than the high normal group. Cox regression analysis confirmed that 1-year serum albumin was inversely associated with the risk of graft loss (hazard ratio [HR] 0.414, 95% confidence interval [CI] 0.200-0.856), patient death (HR 0.097, 95% CI 0.019-0.484), and CV events (HR 0.228, 95% CI 0.074-0.702). In conclusion, a relatively low 1-year post-transplant serum albumin level within the normal limits (˂4.6g/dL) significantly predicts poor long-term outcomes. | en_US |
dc.language.iso | en | en_US |
dc.publisher | WILEY-BLACKWELL | en_US |
dc.subject | Albumin | en_US |
dc.subject | Kidney transplantation | en_US |
dc.subject | Allograft survival | en_US |
dc.subject | Patient survival | en_US |
dc.subject | Cardiovascular mortality | en_US |
dc.title | Prognostic Significance of 1-Year Serum Albumin Levels Within the Normal Range After Kidney Transplantation | en_US |
dc.type | Article | en_US |
dc.relation.no | 11 | - |
dc.relation.volume | 39 | - |
dc.identifier.doi | 10.1111/aor.12473 | - |
dc.relation.page | 965-972 | - |
dc.relation.journal | ARTIFICIAL ORGANS | - |
dc.contributor.googleauthor | Oh, Il Hwan | - |
dc.contributor.googleauthor | Park, Joon-Sung | - |
dc.contributor.googleauthor | Lee, Chang Hwa | - |
dc.contributor.googleauthor | Kang, Chong Myung | - |
dc.contributor.googleauthor | Kim, Gheun-Ho | - |
dc.relation.code | 2015000287 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | kimgh | - |
dc.identifier.orcid | http://orcid.org/0000-0002-8445-9892 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.