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dc.contributor.author김근호-
dc.date.accessioned2017-09-06T00:37:23Z-
dc.date.available2017-09-06T00:37:23Z-
dc.date.issued2015-11-
dc.identifier.citationARTIFICIAL ORGANS, v. 39, NO 11, Page. 965-972en_US
dc.identifier.issn0160-564X-
dc.identifier.issn1525-1594-
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1111/aor.12473/abstract;jsessionid=722CB9777785F12B023F974A22343FCE.f03t03-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/28918-
dc.description.abstractHypoalbuminemia is associated with poor outcomes in kidney transplantation (KT). However, what level is optimal in serum albumin is not clear for the long-term prognosis. To determine whether the long-term outcomes are different even between the normal ranges of serum albumin after KT, we analyzed data from 404 renal allograft recipients whose 1-year post-transplant serum albumin levels were within the normal limits (3.5-5.5g/dL). During a follow-up of 122 +/- 56 months, 97 graft losses, 20 patient deaths, and 50 cardiovascular (CV) events occurred. Based on 1-year serum albumin levels, the patients were divided into high normal (4.6g/dL, n=209) and low normal (˂4.6g/dL, n=195) groups. Kaplan-Meier analyses revealed that the low normal group had poorer allograft survival (P=0.01), patient survival (P˂0.001), and CV event-free survival (P˂0.001) than the high normal group. Cox regression analysis confirmed that 1-year serum albumin was inversely associated with the risk of graft loss (hazard ratio [HR] 0.414, 95% confidence interval [CI] 0.200-0.856), patient death (HR 0.097, 95% CI 0.019-0.484), and CV events (HR 0.228, 95% CI 0.074-0.702). In conclusion, a relatively low 1-year post-transplant serum albumin level within the normal limits (˂4.6g/dL) significantly predicts poor long-term outcomes.en_US
dc.language.isoenen_US
dc.publisherWILEY-BLACKWELLen_US
dc.subjectAlbuminen_US
dc.subjectKidney transplantationen_US
dc.subjectAllograft survivalen_US
dc.subjectPatient survivalen_US
dc.subjectCardiovascular mortalityen_US
dc.titlePrognostic Significance of 1-Year Serum Albumin Levels Within the Normal Range After Kidney Transplantationen_US
dc.typeArticleen_US
dc.relation.no11-
dc.relation.volume39-
dc.identifier.doi10.1111/aor.12473-
dc.relation.page965-972-
dc.relation.journalARTIFICIAL ORGANS-
dc.contributor.googleauthorOh, Il Hwan-
dc.contributor.googleauthorPark, Joon-Sung-
dc.contributor.googleauthorLee, Chang Hwa-
dc.contributor.googleauthorKang, Chong Myung-
dc.contributor.googleauthorKim, Gheun-Ho-
dc.relation.code2015000287-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidkimgh-
dc.identifier.orcidhttp://orcid.org/0000-0002-8445-9892-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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