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dc.contributor.author조석현-
dc.date.accessioned2017-05-02T01:16:52Z-
dc.date.available2017-05-02T01:16:52Z-
dc.date.issued2015-08-
dc.identifier.citationANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, v. 124, NO 8, Page. 663-670en_US
dc.identifier.issn0003-4894-
dc.identifier.issn1943-572X-
dc.identifier.urihttp://journals.sagepub.com/doi/abs/10.1177/0003489415576181-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/27108-
dc.description.abstractObjectives: To investigate the impact of olfactory dysfunction on quality of life (QOL) and psychological status in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: A retrospective observational study was conducted from January 2011 to May 2012 with 130 patients with septal deviation (SD) (n = 59) and CRSwNP (n = 71). All patients underwent computed tomography (CT), allergy tests, and sniffin' stick olfactory test. Anosmia was defined by Threshold-Discrimination-Identification (TDI) scores less than 16. QOL and psychological symptoms were assessed with the Sinonasal Outcome Test-20 (SNOT-20) and Symptom Checklist-90-Revised (SCL-90-R). Results: Odor discrimination and identification scores were significantly lower in CRSwNP than in SD (P = .008 and P = .005, respectively). In CRSwNP, identification score decreased with higher CT score (r = -0.29, P = .014). CRSwNP with anosmia showed a decreased QOL (P = .044), and SNOT-20 negatively correlated with TDI in severe CRSwNP (CT score 15, r = -0.714, P = .001). Anosmia patients had higher anxiety and phobia scores of SCL-90-R in both SD and CRSwNP. However, depression score increased only in CRSwNP with anosmia (P = .025). Conclusion: Olfactory dysfunction may have significant effects on QOL and psychological health. CRSwNP with anosmia is a distinct phenotype having mixed type of olfactory loss that might have a detrimental effect on depression.en_US
dc.description.sponsorshipThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported by the Basic Science Research Program of the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (NRF-2013R1A1A2007651). Role of the Sponsor: Research Foundation of Korea had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publicationen_US
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS INCen_US
dc.subjectnasal obstructionen_US
dc.subjectnasal polyposisen_US
dc.subjectolfactionen_US
dc.subjectotolaryngologyen_US
dc.subjectrhinologyen_US
dc.subjectsinusitisen_US
dc.titleAltered Quality of Life and Psychological Health (SCL-90-R) in Patients With Chronic Rhinosinusitis With Nasal Polypsen_US
dc.typeArticleen_US
dc.relation.no8-
dc.relation.volume124-
dc.identifier.doi10.1177/0003489415576181-
dc.relation.page663-670-
dc.relation.journalANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY-
dc.contributor.googleauthorChung, Jae Ho-
dc.contributor.googleauthorLee, Yun Jae-
dc.contributor.googleauthorKang, Tae Wook-
dc.contributor.googleauthorKim, Kyung Rae-
dc.contributor.googleauthorJang, Dong Pyo-
dc.contributor.googleauthorKim, In Young-
dc.contributor.googleauthorCho, Seok Hyun-
dc.relation.code2015000092-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidshcho-
dc.identifier.researcherIDF-6753-2017-
dc.identifier.orcidhttp://orcid.org/0000-0001-8218-5894-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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