Does Lymphocytic Colitis Always Present with Normal Endoscopic Findings?

Title
Does Lymphocytic Colitis Always Present with Normal Endoscopic Findings?
Authors
한동수
Keywords
Lymphocytic colitis; Hypervascularity; Exudative; Hemorrhage
Issue Date
2015-03
Publisher
EDITORIAL OFFICE GUT & LIVER
Citation
GUT AND LIVER, v. 9, NO 2, Page. 197-201
Abstract
Background/Aims: Although normal endoscopic findings are, as a rule, part of the diagnosis of microscopic colitis, several cases of macroscopic lesions (MLs) have been reported in collagenous colitis, but. hardly in lymphocytic colitis (LC). The aim of this study was to investigate the endoscopic, clinical, and histopathologic features of LC with MLs. Methods: A total of 14 patients with LC who were diagnosed between 2005 and 2010 were enrolled in the study. Endoscopic, clinical, and histopathologic findings were compared retrospectively according to the presence or absence of MLs. Results: MLs were observed in seven of the 14 LC cases. Six of the MLs exhibited hypervascularity, three exhibited exudative bleeding and one exhibited edema. The patients with MLs had more severe diarrhea and were taking aspirin or proton pump inhibitors. More intraepithelial lymphocytes were observed during histologic examination in the patients with MLs compared to the patients without MLs, although this difference was not significant. The numbers of mononuclear cells and neutrophils in the lamina propria were independent of the presence or absence of MLs. Conclusions: LC does not always present with normal endoscopic findings. Hypervascularity and exudative bleeding are frequent endoscopic findings in patients with MLs.
URI
http://www.gutnliver.org/journal/view.html?volume=9&number=2&spage=197&year=2015http://hdl.handle.net/20.500.11754/22720
ISSN
1976-2283; 2005-1212
DOI
http://dx.doi.org/10.5009/gnl13373
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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