Seasonality of Gout in Korea: A Multicenter Study

Title
Seasonality of Gout in Korea: A Multicenter Study
Authors
전재범
Keywords
Gout Onset; Flares; Seasonality; Summer; Korea
Issue Date
2015-03
Publisher
KOREAN ACAD MEDICAL SCIENCES
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v. 30, NO 3, Page. 240-244
Abstract
The object of this study was to evaluate the seasonality of gout in Korea. We retrospectively examined data from 330 patients seen at nine rheumatology clinics, treated with urate lowering therapy (ULT) more than one year after stopping prophylactic medication. Demographic data, clinical and laboratory features, and seasonality of gout onset and flares were collected. Season was classified in three- month intervals. The mean age was 52.2 yr and mean disease duration was 26.8 months. The male to female count was 318:12. The onset of acute gouty attacks was obtained in 256 patients. Gout developed most commonly in summer season (36.7%) (P ˂ 0.001) and in June (15.6%, P = 0.002). During ULT, there were 147 (male 97.3%) gout flares. Although there was no statistically significant difference, gout flares were more common in summer (30.6%). Aggravating factors were identified in 57 flares: alcohol (72.0%) was most common. In the patients who attained target serum uric acid (˂ 6 mg/dL) at the end of prophylaxis, gout flares were high in fall (35.8%) and September (17.0%). In Korea, the summer is most common season of gout onset and there is a tendency for gout flares to increase during ULT in summer/fall season.
URI
http://synapse.koreamed.org/search.php?where=aview&id=10.3346/jkms.2015.30.3.240&code=0063JKMS&vmode=FULLhttp://hdl.handle.net/20.500.11754/22558
ISSN
1011-8934; 1598-6357
DOI
http://dx.doi.org/10.3346/jkms.2015.30.3.240
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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