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dc.contributor.author상병인-
dc.date.accessioned2016-08-05T02:22:14Z-
dc.date.available2016-08-05T02:22:14Z-
dc.date.issued2015-02-
dc.identifier.citationPROCESS BIOCHEMISTRY, v. 50, NO 4, Page. 630-635en_US
dc.identifier.issn1359-5113-
dc.identifier.issn1873-3298-
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S1359511315000537-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/22446-
dc.description.abstractLignocellulosic degradation compounds, especially phenolic compounds, inhibit the fermentation of Clostridium strains. In this study, a simple in situ detoxification method using a surfactant was developed for butyric acid production by Clostridium tyrobutyricum ATCC25755. Tween 80, a non-ionic surfactant, was chosen to sequester inhibitors by forming micelles, consequently preventing direct contact of inhibitors with cell membranes. When Tween 80 was added during fermentation, butyric acid production was significantly enhanced in the presence of hydrophobic phenolics such as p-coumaric acid (0 vs. 3.1 g/L butyric acid) and ferulic acid (2.2 vs. 4.6 g/L butyric acid) even at 0.016 g/L of Tween 80 (corresponding to the critical micelle concentration). Lignin, a polyphenol compound in lignocellulose, was also detoxified by Tween 80. When Tween 80 was added to acid-pretreated rice straw hydrolysate, butyric acid production significantly increased (0.1 vs. 8.7 g/L butyric acid), thus verifying detoxification effect of Tween 80 on lignocellulosic hydrolysate. (C) 2015 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipKorea Ministry of Environment as "Converging Technology Project" Creative Allied Project (CAP) of the Korea Research Council of Fundamental Science and Technology (KRCF)/Korea Institute of Science and Technology (KIST)en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCI LTDen_US
dc.subjectButyric aciden_US
dc.subjectLignocelluloseen_US
dc.subjectPhenolic compounden_US
dc.subjectIn situ detoxificationen_US
dc.subjectTween 80en_US
dc.titleIn situ detoxification of lignocellulosic hydrolysate using a surfactant for butyric acid production by Clostridium tyrobutyricum ATCC 25755en_US
dc.typeArticleen_US
dc.relation.no4-
dc.relation.volume50-
dc.identifier.doi10.1016/j.procbio.2015.01.020-
dc.relation.page630-635-
dc.relation.journalPROCESS BIOCHEMISTRY-
dc.contributor.googleauthorLee, Kyung Min-
dc.contributor.googleauthorKim, Ki-Yeon-
dc.contributor.googleauthorChoi, Okkyoung-
dc.contributor.googleauthorWoo, Han Min-
dc.contributor.googleauthorKim, Yunje-
dc.contributor.googleauthorHan, Sung Ok-
dc.contributor.googleauthorSang, Byoung-In-
dc.contributor.googleauthorUm, Youngsoon-
dc.relation.code2015001287-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF ENGINEERING[S]-
dc.sector.departmentDEPARTMENT OF CHEMICAL ENGINEERING-
dc.identifier.pidbiosang-
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COLLEGE OF ENGINEERING[S](공과대학) > CHEMICAL ENGINEERING(화학공학과) > Articles
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