Hazardous Drinking-Related Characteristics of Depressive Disorders in Korea: The CRESCEND Study

Title
Hazardous Drinking-Related Characteristics of Depressive Disorders in Korea: The CRESCEND Study
Authors
박용천
Keywords
Depressive Disorders; Hazardous Drinking; Suicidal Ideation; Smoking; Hypochondriasis
Issue Date
2015-01
Publisher
KOREAN ACAD MEDICAL SCIENCES
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v. 30, NO 1, Page. 74-81
Abstract
This study aimed to identify clinical correlates of hazardous drinking in a large cohort of Korean patients with depression. We recruited a total of 402 depressed patients aged ˃ 18 yr from the Clinical Research Center for Depression (CRESCEND) study in Korea. Patients' drinking habits were assessed using the Korean Alcohol Use Disorder Identification Test (AUDIT-K). Psychometric scales, including the HAMD, HAMA, BPRS, CGI-S, SSI-Beck, SOFAS, and WHOQOL-BREF, were used to assess depression, anxiety, overall psychiatric symptoms, global severity, suicidal ideation, social functioning, and quality of life, respectively. We compared demographic and clinical features and psychometric scores between patients with and without hazardous drinking behavior after adjusting for the effects of age and sex. We then performed binary logistic regression analysis to identify independent correlates of hazardous drinking in the study population. Our results revealed that hazardous drinking was associated with current smoking status, history of attempted suicide, greater psychomotor retardation, suicidal ideation, weight loss, and lower hypochondriasis than non-hazardous drinking. The regression model also demonstrated that more frequent smoking, higher levels of suicidal ideation, and lower levels of hypochondriasis were independently correlates for hazardous drinking in depressed patients. In conclusion, depressed patients who are hazardous drinkers experience severer symptoms and a greater burden of illness than non-hazardous drinkers. In Korea, screening depressed patients for signs of hazardous drinking could help identify subjects who may benefit from comprehensive therapeutic approaches.
URI
http://hdl.handle.net/20.500.11754/20961https://synapse.koreamed.org/DOIx.php?id=10.3346/jkms.2015.30.1.74
ISSN
1011-8934
DOI
http://dx.doi.org/10.3346/jkms.2015.30.1.74
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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