Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 채필석 | - |
dc.date.accessioned | 2022-10-31T00:41:01Z | - |
dc.date.available | 2022-10-31T00:41:01Z | - |
dc.date.issued | 2019-02 | - |
dc.identifier.citation | Sensors and Actuators, B: Chemical, v. 281, Page. 933-944 | en_US |
dc.identifier.issn | 0925-4005 | en_US |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0925400518319774?via%3Dihub | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/176098 | - |
dc.description.abstract | Six thiophene-bis(benzimidazole)-based molecular probes with tunable fluorescence emission were synthesized for selective Hg2+ detection. Probe 1 contains a thiophene-bis(benzimidazole) unit without an appendage, while probes 2-4 have multiple appendages on benzimidazole rings of the core and probe 6/7 has two biphenyl appendages on the thiophene ring. Fluorescence emissions of all these probes were selectively quenched upon Hg2+ addition, but probe 7 provided the most sensitive detection of Hg2+, giving the highest association constant (K-a (7) = 2.38 x 10(6) M-1) and the lowest observed and calculated limit of detections (LODs) (5 nM and 0.047 pM, respectively). Thus, the probe 7-Hg2+ complex was further tested for detection of a biomolecule as a next step. Among the various biomolecules tested (including amino acids), L-lysine (Lys) uniquely showed a full restoration of the fluorescence intensity of [probe 7 + Hg2+ (1:2)]-complex to the level of the free probe, with an LOD of 5 nM. Thus, a cascade detection of Hg2+ and Lys was attained by probe 7 via selective quenching and recovering of the fluorescence intensity, which enables us to build an "ON-OFF-ON" switch and logic gate at a molecular level. The current system was fully studied by various analytical methods such as UV-vis, fluorescence, and H-1 NMR spectroscopies, IR, FE-SEM images, and DFT calculations. | en_US |
dc.description.sponsorship | This work was supported by the research fund of Hanyang University (HY-2018-N). | en_US |
dc.language | en | en_US |
dc.publisher | Elsevier BV | en_US |
dc.subject | Thiophene-bis(benzimidazole) | en_US |
dc.subject | Hg2+ | en_US |
dc.subject | Lysine | en_US |
dc.subject | ON-OFF-ON | en_US |
dc.subject | Switch | en_US |
dc.subject | Logic gate | en_US |
dc.title | Fluorescence tunable thiophene-bis(benzimidazole)-based probes for a cascade trace detection of Hg2+ and lysine: A molecular switch mimic | en_US |
dc.type | Article | en_US |
dc.relation.volume | 281 | - |
dc.identifier.doi | 10.1016/j.snb.2018.11.023 | en_US |
dc.relation.page | 933-944 | - |
dc.relation.journal | Sensors and Actuators, B: Chemical | - |
dc.contributor.googleauthor | Kumar, Ashwani | - |
dc.contributor.googleauthor | Chae, Pil Seok | - |
dc.sector.campus | E | - |
dc.sector.daehak | 공학대학 | - |
dc.sector.department | 생명나노공학과 | - |
dc.identifier.pid | pchae | - |
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