Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이철훈 | - |
dc.date.accessioned | 2022-06-28T06:54:49Z | - |
dc.date.available | 2022-06-28T06:54:49Z | - |
dc.date.issued | 1999-10 | - |
dc.identifier.citation | In: Journal of Microbiology and Biotechnology. (Journal of Microbiology and Biotechnology, October 1999, 9(5):672-674) | en_US |
dc.identifier.issn | 10177825 | - |
dc.identifier.uri | https://www.koreascience.or.kr/article/JAKO199911922245309.page | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/171476 | - |
dc.description.abstract | Cepacidine A was first identified as a novel antifungal antibiotic which was isolated from the culture broth of Pseudomonas cepacia AF2001. It showed a potent in vitro antifungal activity against various pathogenic fungi, but did not show any activity against bacteria. Recently, the immunosuppressive action of cepacidine A was discovered using an in vitro screening system involving inhibition of the proliferation of murine lymphocytes stimulated by 2 mitogens, and also by in. vivo mouse models involving inhibition of delayed type hypersensitivity and SRBC hemagglutination. Cepacidine A showed a significant activity of cellular immunosuppression (ED50) at concentration levels of 1-3 mg/kg, i.p.. Unfortunately, the delayed toxicity at a dose of above 3 mg/kg i.p. was apparent. | en_US |
dc.language.iso | en | en_US |
dc.publisher | KSAM, Springer Verlag | en_US |
dc.subject | Antifungal antibiotic | en_US |
dc.subject | cepacidine A | en_US |
dc.subject | immunosuppressive activity | en_US |
dc.title | Immunosuppressive Activity of Cepacidine A, a Novel Antifungal Antibiotic Produced by Pseudomonas cepacia | en_US |
dc.type | Article | en_US |
dc.relation.journal | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.contributor.googleauthor | Lee, Chul-Hoon | - |
dc.contributor.googleauthor | Suh, Jung-Woo | - |
dc.contributor.googleauthor | Cho, Youl-Hee | - |
dc.relation.code | 2008205425 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF PHARMACY[E] | - |
dc.sector.department | DEPARTMENT OF PHARMACY | - |
dc.identifier.pid | chhlee | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.