Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이철훈 | - |
dc.date.accessioned | 2021-02-17T23:52:14Z | - |
dc.date.available | 2021-02-17T23:52:14Z | - |
dc.date.issued | 2001-02 | - |
dc.identifier.citation | Journal of Microbiology and Biotechnology, v. 11, issue. 1, page. 138-142 | en_US |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.issn | 1738-8872 | - |
dc.identifier.uri | http://www.koreascience.kr/article/JAKO200111920816699.page | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/158660 | - |
dc.description.abstract | During the course of searching for anti-allergic substances from unexplored plant sources, an inhibitor of leukotriene D 4 -induced tracheal contraction was isolated from Euphoribia helioscopia. This isolated polyphenol compound, known as helioscopinin-A, showed a certain inhibitory activity on capillary permeability in passive cutaneous anaphylaxis responses of rats and also on antigen-induced bronchial constriction in an experimental asthma model of guinea pigs. The compound at a high concentration weakly inhibited histamine release from isolated mast cells of rats. It is suggested that this compound is an anti-allergic and anti-asthmatic which exerts its activity through antagonism on leukotrene D 4 -induced responses. A partial inhibition of allergic mediator relase may also bee involved. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | The Korean Society for Microbiology and Biotechnology | en_US |
dc.subject | Euphorbia helioscopia | en_US |
dc.subject | helioscopinin-A | en_US |
dc.subject | anti-allergy | en_US |
dc.subject | antiasthma | en_US |
dc.title | Anti-allergic and anti-asmatic activity of heliscopinin-A, a polyphenol compound, isolated from Euphorbia heliscopia. | en_US |
dc.type | Article | en_US |
dc.relation.journal | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.contributor.googleauthor | Park, Kwan-Ha | - |
dc.contributor.googleauthor | Koh, Dong-Soo | - |
dc.contributor.googleauthor | Jung, Ill-Min | - |
dc.contributor.googleauthor | Lee, Chul-Hoon | - |
dc.contributor.googleauthor | Kim, Kye-Hoon | - |
dc.contributor.googleauthor | Lim, Yoong-Ho | - |
dc.relation.code | 2008205425 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF PHARMACY[E] | - |
dc.sector.department | DEPARTMENT OF PHARMACY | - |
dc.identifier.pid | chhlee | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.