한국인에서 기능성 소화불량증의 유병률 및 양태 : 로마 II 기준과 로마 III 기준에 의한 표본인구 설문조사

Abstract

ABSTRACT

Prevalence and Sociodemography of Functional dyspepsia in Korea : A population-based survey using Rome II and Rome III diagnostic criteria

Hyung Tae Kim, M.D. Department of Medical Science, Graduate School, Hanyang University (Directed by Prof. Oh Young Lee, M.D., Ph.D.)

Objective: Functional dyspepsia(FD) is one of the most frequently observed disorders in clinical practice. The prevalence of FD shows great variation according to diagnostic criteria, race, gender, age, and environmental factors. Currently, there are a few studies about diagnosis of FD using Rome III criteria, which is newly developed. The aim of this study is to estimate the prevalence and sociodemography(sex, age, region, job, educational status, income status) of uninvestigated FD in Korea by using Rome II and Rome III diagnostic criteria. Methods: The telephone interview survey was conducted by Gallup, Korea using a validated questionnaire in 2007. A random sample of gender and age (between 15 and 60 years), based on a per capita ratio was obtained. Results: The response rate of the telephone interview survey was 25%(n=1009, 501 males and 508 females). The prevalence of FD by Rome II criteria is 9.0% (91 people). Females (10.0%) in these people are more than males (8.0%). The prevalence of FD according to the Rome II criteria based on the age distribution, educational level, job, income status and living area was not statistically different. The prevalence of FD by Rome III criteria is 13.4% (135 people). Females (15.2%) who met the Rome III criteria are more than males (11.6%). The prevalence of FD according to the Rome III criteria, based on the age distribution, educational level, job, income and living area was not significantly different. The prevalence of subgroups by Rome III criteria are postprandial discomfort syndrome (PDS) (47%), epigastric pain syndrome (EPS) (26%), and people who has postprandial discomfort syndrome and epigastric pain syndrome(27%). We have divided three groups in functional dyspepsia. Group A is compatible with Rome II but not with Rome III. Group B is fulfilled by Rome III but not by Rome II. Group C is fit for Rome II and Rome III. We analyzed the prevalence and sociodemographic feature of each group. Group A is highly prevalent in under 40 ages ( p = 0.003 ). Other sociodemographic features about gender, area, job, educational level and income status are not significantly different. Conclusion: The prevalence of FD in Korean population is 13.4% by Rome III criteria, and 9.0% by Rome II criteria. In the FD, females are higher prevalence than males. The prevalence of PDS is higher than EPS. Group A is highly prevalent in under 40 ages.