Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 문성용 | - |
dc.date.accessioned | 2019-12-10T00:44:06Z | - |
dc.date.available | 2019-12-10T00:44:06Z | - |
dc.date.issued | 2018-11 | - |
dc.identifier.citation | JOURNAL OF CHROMATOGRAPHY A, v. 1579, page. 49-59 | en_US |
dc.identifier.issn | 0021-9673 | - |
dc.identifier.issn | 1873-3778 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0021967318312925?via%3Dihub | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/120543 | - |
dc.description.abstract | If a multi-component monosugar mixture including fucose was used as the substrates for the Klebsiella oxytoca fermentation, it could offer the following two benefits simultaneously; (i) the removal of all monosugars other than fucose, and (ii) the acquisition of 2,3-butanediol (BD). To utilize such two benefits in favor of the economical efficiency of the fucose production process, it is essential to accomplish a high purity separation between fucose and BD on the basis of a highly -economical mode. To address this issue, we aimed to develop a simulated moving bed (SMB) process for continuous-mode separation of fucose and BD with high purities. It was first found that an Amberchrom-CG71C resin could become a suitable adsorbent for the separation of interest. The intrinsic parameters of fucose and BD on such proven adsorbent were determined, and then applied to the optimal design of the fucose-BD separation SMB. The capability of the designed SMB in ensuring high purities and high yields was experimentally verified. Finally, we devised two potential strategies to make a further improvement in product concentrations and/or desorbent usage while keeping the purities and yields of fucose and BD almost unchanged. The first strategy was based on partial extract-collection and partial extract-discard, which was found to result in 33% higher BD product concentration. The second strategy was based on partial extract-collection, partial extract-recycle, and partial desorbent-port closing, which could lead to 25% lower desorbent usage, 33% higher BD product concentration, and 7% higher fucose product concentration. (C) 2018 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (grant number NRF-2015R1A2A2A01003455). Also, it was partially supported by the Advanced Biomass R&D Center (ABC) of Global Frontier Project funded by the Ministry of Science, ICT and Future Planning (ABC 2010-0029728). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ELSEVIER SCIENCE BV | en_US |
dc.subject | Simulated moving bed | en_US |
dc.subject | Fucose | en_US |
dc.subject | 2,3-butanediol | en_US |
dc.subject | Continuous separation | en_US |
dc.subject | Operation strategies | en_US |
dc.title | Continuous-mode separation of fucose and 2,3-butanediol using a three-zone simulated moving bed process and its performance improvement by using partial extract-collection, partial extract-recycle, and partial desorbent-port closing | en_US |
dc.type | Article | en_US |
dc.relation.volume | 1579 | - |
dc.identifier.doi | 10.1016/j.chroma.2018.10.029 | - |
dc.relation.page | 49-59 | - |
dc.relation.journal | JOURNAL OF CHROMATOGRAPHY A | - |
dc.contributor.googleauthor | Lee, Chung-Gi | - |
dc.contributor.googleauthor | Jo, Cheol Yeon | - |
dc.contributor.googleauthor | Song, Ye Jin | - |
dc.contributor.googleauthor | Mun, Sungyong | - |
dc.relation.code | 2018003295 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF CHEMICAL ENGINEERING | - |
dc.identifier.pid | munsy | - |
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