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dc.contributor.author문성용-
dc.date.accessioned2019-12-10T00:44:06Z-
dc.date.available2019-12-10T00:44:06Z-
dc.date.issued2018-11-
dc.identifier.citationJOURNAL OF CHROMATOGRAPHY A, v. 1579, page. 49-59en_US
dc.identifier.issn0021-9673-
dc.identifier.issn1873-3778-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0021967318312925?via%3Dihub-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/120543-
dc.description.abstractIf a multi-component monosugar mixture including fucose was used as the substrates for the Klebsiella oxytoca fermentation, it could offer the following two benefits simultaneously; (i) the removal of all monosugars other than fucose, and (ii) the acquisition of 2,3-butanediol (BD). To utilize such two benefits in favor of the economical efficiency of the fucose production process, it is essential to accomplish a high purity separation between fucose and BD on the basis of a highly -economical mode. To address this issue, we aimed to develop a simulated moving bed (SMB) process for continuous-mode separation of fucose and BD with high purities. It was first found that an Amberchrom-CG71C resin could become a suitable adsorbent for the separation of interest. The intrinsic parameters of fucose and BD on such proven adsorbent were determined, and then applied to the optimal design of the fucose-BD separation SMB. The capability of the designed SMB in ensuring high purities and high yields was experimentally verified. Finally, we devised two potential strategies to make a further improvement in product concentrations and/or desorbent usage while keeping the purities and yields of fucose and BD almost unchanged. The first strategy was based on partial extract-collection and partial extract-discard, which was found to result in 33% higher BD product concentration. The second strategy was based on partial extract-collection, partial extract-recycle, and partial desorbent-port closing, which could lead to 25% lower desorbent usage, 33% higher BD product concentration, and 7% higher fucose product concentration. (C) 2018 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipThis research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (grant number NRF-2015R1A2A2A01003455). Also, it was partially supported by the Advanced Biomass R&D Center (ABC) of Global Frontier Project funded by the Ministry of Science, ICT and Future Planning (ABC 2010-0029728).en_US
dc.language.isoen_USen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.subjectSimulated moving beden_US
dc.subjectFucoseen_US
dc.subject2,3-butanediolen_US
dc.subjectContinuous separationen_US
dc.subjectOperation strategiesen_US
dc.titleContinuous-mode separation of fucose and 2,3-butanediol using a three-zone simulated moving bed process and its performance improvement by using partial extract-collection, partial extract-recycle, and partial desorbent-port closingen_US
dc.typeArticleen_US
dc.relation.volume1579-
dc.identifier.doi10.1016/j.chroma.2018.10.029-
dc.relation.page49-59-
dc.relation.journalJOURNAL OF CHROMATOGRAPHY A-
dc.contributor.googleauthorLee, Chung-Gi-
dc.contributor.googleauthorJo, Cheol Yeon-
dc.contributor.googleauthorSong, Ye Jin-
dc.contributor.googleauthorMun, Sungyong-
dc.relation.code2018003295-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF ENGINEERING[S]-
dc.sector.departmentDEPARTMENT OF CHEMICAL ENGINEERING-
dc.identifier.pidmunsy-
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > CHEMICAL ENGINEERING(화학공학과) > Articles
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